Publikationen

2023

Harries M, Jaeger VK, Rodiah I, Hassenstein MJ, Ortmann J, Dreier M, von Holt I, Brinkmann M, Dulovic A, Gornyk D, Hovardovska O, Kuczewski C, Kurosinski MA, Schlotz M, Schneiderhan-Marra N, Strengert M, Krause G, Sester M, Klein F, Petersmann A, Karch A, Lange B. Bridging the gap - estimation of 2022/2023 SARS-CoV-2 healthcare burden in Germany based on multidimensional data from a rapid epidemic panel. Int J Infect Dis 2023. PubMed

Weber T, Dähling S, Rose S, Affeldt P, Vanshylla K, Ullrich L, Gieselmann L, Teipel F, Gruell H, Di Cristanziano V, Kim DS, Georgiou G, Koch M, Kreer C, Klein F. Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool. Sci Immunol 2023; 8(89): eadk5845. PubMed

Zehner M, Alt M, Ashurov A, Goldsmith JA, Spies R, Weiler N, Lerma J, Gieselmann L, Stöhr D, Gruell H, Schultz EP, Kreer C, Schlachter L, Janicki H, Laib Sampaio K, Stegmann C, Nemetchek MD, Dähling S, Ullrich L, Dittmer U, Witzke O, Koch M, Ryckman BJ, Lotfi R, McLellan JS, Krawczyk A, Sinzger C, Klein F. Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer. Immunity 2023; 56(11): 2602-20.e10. PubMed

Schommers P, Kim DS, Schlotz M, Kreer C, Eggeling R, Hake A, Stecher M, Park J, Radford CE, Dingens AS, Ercanoglu MS, Gruell H, Odidika S, Dahlhaus M, Gieselmann L, Ahmadov E, Lawong RY, Heger E, Knops E, Wyen C, Kümmerle T, Römer K, Scholten S, Wolf T, Stephan C, Suárez I, Raju N, Adhikari A, Esser S, Streeck H, Duerr R, Nanfack AJ, Zolla-Pazner S, Geldmacher C, Geisenberger O, Kroidl A, William W, Maganga L, Ntinginya NE, Georgiev IS, Vehreschild JJ, Hoelscher M, Fätkenheuer G, Lavinder JJ, Bloom JD, Seaman MS, Lehmann C, Pfeifer N, Georgiou G, Klein F. Dynamics and durability of HIV-1 neutralization are determined by viral replication. Nat Med 2023; 29(11): 2763-74. PubMed

Bellerba F, Bardeck N, Boehm M, D'Ecclesiis O, Raimondi S, Tomezzoli E, Miranda MS, Alves IM, Alves D, Abecasis A, Gabellone V, Gabrielli E, Vaglio G, Shamsara E, Pfeifer N, Mommo C, Incardona F, Kaiser R, Gandini S. SARS-CoV-2 trends in Italy, Germany and Portugal and school opening during the period of Omicron variant dominance: a quasi-experimental study. Int J Infect Dis 2023. PubMed

Kreer C, Lupo C, Ercanoglu MS, Gieselmann L, Spisak N, Grossbach J, Schlotz M, Schommers P, Gruell H, Dold L, Beyer A, Nourmohammad A, Mora T, Walczak AM, Klein F. Probabilities of developing HIV-1 bNAb sequence features in uninfected and chronically infected individuals. Nat Commun 2023; 14(1): 7137. PubMed

Simonis A, Kreer C, Albus A, Rox K, Yuan B, Holzmann D, Wilms JA, Zuber S, Kottege L, Winter S, Meyer M, Schmitt K, Gruell H, Theobald SJ, Hellmann AM, Meyer C, Ercanoglu MS, Cramer N, Munder A, Hallek M, Fätkenheuer G, Koch M, Seifert H, Rietschel E, Marlovits TC, van Koningsbruggen-Rietschel S, Klein F, Rybniker J. Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa. Cell 2023; 186(23): 5098-113.e19. PubMed

Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald SJ, Simonis A, Di Cristanziano V, Gieselmann L, Dewald F, Lehmann C, Augustin M, Klein F, Alcazar MAA, Rongisch R, Fabri M, Rybniker J, Goebel H, Stetefeld J, Brachvogel B, Cursiefen C, Koch M, Bock F. The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. J Mol Cell Biol 2023. PubMed

Stab V, Stahl-Hennig C, Ensser A, Richel E, Fraedrich K, Sauermann U, Tippler B, Klein F, Burton DR, Tenbusch M, Überla K. HIV-1 neutralizing antibodies provide sterilizing immunity by blocking infection of the first cells. Cell Rep Med 2023; 4(10): 101201. PubMed

Gruell H, Schommers P. Advancing bnAb combinations for HIV prevention. Lancet HIV 2023; 10(10): e625-e6. PubMed

Augustin M, Stecher M, Wüstenberg H, Di Cristanziano V, Sandaradura de Silva U, Picard LK, Pracht E, Rauschning D, Gruell H, Klein F, Wenisch C, Hallek M, Schommers P, Lehmann C. 15-month post-COVID syndrome in outpatients: Attributes, risk factors, outcomes, and vaccination status - longitudinal, observational, case-control study. Front Immunol 2023; 14: 1226622. PubMed

Spiertz A, Tsakmaklis A, Farowski F, Knops E, Heger E, Wirtz M, Kaiser R, Holtick U, Vehreschild M, Di Cristanziano V. Torque teno virus-DNA load as individual cytomegalovirus risk assessment parameter upon allogeneic hematopoietic stem cell transplantation. Eur J Haematol 2023; 111(6): 963-9. PubMed

Elén S, Björkman P, Zazzi M, Böhm M, Bernal E, Sönnerborg A, Elvstam O. Low-level HIV viraemia during antiretroviral therapy: Longitudinal patterns and predictors of viral suppression. HIV Med 2023. PubMed

Schmidle P, Leson S, Wieland U, Böer-Auer A, Metze D, Braun SA. Lives of Skin Lesions in Monkeypox: Histomorphological, Immunohistochemical, and Clinical Correlations in a Small Case Series. Viruses 2023; 15(8). PubMed

Rauschning D, Ehren I, Heger E, Knops E, Fätkenheuer G, Suárez I, Lehmann C. Optimizing Antiretroviral Therapy in Heavily ART-Experienced Patients with Multi-Class Resistant HIV-1 Using Proviral DNA Genotypic Resistance Testing. Viruses 2023; 15(7). PubMed

Perlejewski K, Radkowski M, Rydzanicz M, Dzieciątkowski T, Silling S, Wieczorek M, Makowiecki M, Horban A, Laskus T. Metagenomic search of viral coinfections in herpes simplex encephalitis patients. J Neurovirol 2023. PubMed

Schweitzer F, Laurent S, Cortese I, Fink GR, Silling S, Skripuletz T, Metz I, Wattjes MP, Warnke C. Progressive Multifocal Leukoencephalopathy: Pathogenesis, Diagnostic Tools, and Potential Biomarkers of Response to Therapy. Neurology 2023. PubMed

Hoboth P, Sztacho M, Quaas A, Akgül B, Hozák P. Quantitative super-resolution microscopy reveals the differences in the nanoscale distribution of nuclear phosphatidylinositol 4,5-bisphosphate in human healthy skin and skin warts. Front Cell Dev Biol 2023; 11: 1217637. PubMed

Pilatz A, Arneth B, Kaiser R, Heger E, Pirkl M, Böttcher S, Fritzenwanker M, Renz H, Mankertz A, Schuppe HC, Wagenlehner F. Acute orchitis deciphered: Coxsackievirus B strains are the main etiology and their presence in semen is associated with acute inflammation and risk of persistent oligozoospermia. J Med Virol 2023; 95(7): e28970. PubMed

Otte F, Zhang Y, Spagnuolo J, Thielen A, Däumer M, Wiethe C, Stoeckle M, Kusejko K, Klein F, Metzner KJ, Klimkait T. Revealing viral and cellular dynamics of HIV-1 at the single-cell level during early treatment periods. Cell Rep Methods 2023; 3(6): 100485. PubMed

Harms M, Smith N, Han M, Groß R, von Maltitz P, Stürzel C, Ruiz-Blanco YB, Almeida-Hernández Y, Rodriguez-Alfonso A, Cathelin D, Caspar B, Tahar B, Sayettat S, Bekaddour N, Vanshylla K, Kleipass F, Wiese S, Ständker L, Klein F, Lagane B, Boonen A, Schols D, Benichou S, Sanchez-Garcia E, Herbeuval JP, Münch J. Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection. Sci Adv 2023; 9(27): eadf8251. PubMed

Habermann E, Frommert LM, Ghannam K, Nguyen My L, Gieselmann L, Tober-Lau P, Klotsche J, Arumahandi de Silva AN, Ten Hagen A, Zernicke J, Kurth F, Sander LE, Klein F, Burmester GR, Biesen R, Albach FN. Performance of commercial SARS-CoV-2 wild-type and Omicron BA.1 antibody assays compared with pseudovirus neutralization tests. J Clin Virol 2023; 165: 105518. PubMed

Radford CE, Schommers P, Gieselmann L, Crawford KHD, Dadonaite B, Yu TC, Dingens AS, Overbaugh J, Klein F, Bloom JD. Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning. Cell Host Microbe 2023; 31(7): 1200-15.e9. PubMed

Binder R, Hahn A, Eberhardt KA, Hagen RM, Rohde H, Loderstädt U, Feldt T, Sarfo FS, Di Cristanziano V, Kahlfuss S, Frickmann H, Zautner AE. Comparison of the Diagnostic Accuracy of Three Real-Time PCR Assays for the Detection of Arcobacter butzleri in Human Stool Samples Targeting Different Genes in a Test Comparison without a Reference Standard. Microorganisms 2023; 11(5). PubMed

Rossetti B, Incardona F, Di Teodoro G, Mommo C, Saladini F, Kaiser R, Sönnerborg A, Lengauer T, Zazzi M. Cohort Profile: A European Multidisciplinary Network for the Fight against HIV Drug Resistance (EuResist Network). Trop Med Infect Dis 2023; 8(5). PubMed

Eser TM, Baranov O, Huth M, Ahmed MIM, Deák F, Held K, Lin L, Pekayvaz K, Leunig A, Nicolai L, Pollakis G, Buggert M, Price DA, Rubio-Acero R, Reich J, Falk P, Markgraf A, Puchinger K, Castelletti N, Olbrich L, Vanshylla K, Klein F, Wieser A, Hasenauer J, Kroidl I, Hoelscher M, Geldmacher C. Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion. Nat Commun 2023; 14(1): 2952. PubMed

Dewald F, Pirkl M, Paluschinski M, Kühn J, Elsner C, Schulte B, Knüfer J, Ahmadov E, Schlotz M, Oral G, Bernhard M, Michael M, Luxenburger M, Andrée M, Hennies MT, Hafezi W, Müller MM, Kümpers P, Risse J, Kill C, Manegold RK, von Frantzki U, Richter E, Emmert D, Monzon-Posadas WO, Gräff I, Kogej M, Büning A, Baum M, Teipel F, Mochtarzadeh B, Wolff M, Gruell H, Di Cristanziano V, Burst V, Streeck H, Dittmer U, Ludwig S, Timm J, Klein F. Impaired humoral immunity to BQ.1.1 in convalescent and vaccinated patients. Nat Commun 2023; 14(1): 2835. PubMed

Köksal MO, Akgül B. The role of digital health technologies in disaster response. Lancet 2023; 401(10388): 1566-7. PubMed

Malin JJ, Weibel S, Gruell H, Kreuzberger N, Stegemann M, Skoetz N. Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis. J Antimicrob Chemother 2023; 78(7): 1586-98. PubMed

Augustin M, Heyn F, Ullrich S, Sandaradura de Silva U, Albert MC, Linne V, Schlotz M, Schommers P, Pracht E, Horn C, Suarez I, Simonis A, Picard LK, Zoufaly A, Wenisch C, Fätkenheuer G, Gruell H, Klein F, Hallek M, Walczak H, Rybniker J, Theobald SJ, Lehmann C. Immunological fingerprint in coronavirus disease-19 convalescents with and without post-COVID syndrome. Front Med (Lausanne) 2023; 10: 1129288. PubMed

Klussmann JP, Grosheva M, Meiser P, Lehmann C, Nagy E, Szijártó V, Nagy G, Konrat R, Flegel M, Holzer F, Groß D, Steinmetz C, Scherer B, Gruell H, Schlotz M, Klein F, de Aragão PA, Morr H, Al Saleh H, Bilstein A, Russo B, Müller-Scholtz S, Acikel C, Sahin H, Werkhäuser N, Allekotte S, Mösges R. Early intervention with azelastine nasal spray may reduce viral load in SARS-CoV-2 infected patients. Sci Rep 2023; 13(1): 6839. PubMed

Braun T, Pruene A, Darguzyte M, Vom Stein AF, Nguyen PH, Wagner DL, Kath J, Roig-Merino A, Heuser M, Riehm LL, Schneider A, Awerkiew S, Talbot SR, Bleich A, Figueiredo C, Bornhäuser M, Stripecke R. Non-viral TRAC-knocked-in CD19(KI)CAR-T and gp350(KI)CAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency. Front Immunol 2023; 14: 1086433. PubMed

Kuechler AS, Heger E, Wirtz M, Weinhold S, Uhrberg M, Boege F, Schulze-Bosse K. Ex Vivo Immune Responsiveness to SARS-CoV-2 Omicron BA.5.1 Following Vaccination with Unmodified mRNA-Vaccine. Vaccines (Basel) 2023; 11(3). PubMed

Hasche D, Akgül B. Prevention and Treatment of HPV-Induced Skin Tumors. Cancers 2023; 15(6): 1709. PubMed

Rattay S, Hufbauer M, Hoboth P, Sztacho M, Akgül B. Viruses and phospholipids: Friends and foes during infection. J Med Virol 2023. PubMed

Kreuter A, Müller VL, Schaller J, Heger E, Wieland U. Anogenital herpes simplex virus infection clinically indistinguishable from mpox. J Med Virol 2023. PubMed

Malin JJ, Suárez I, Biehl LM, Schommers P, Knops E, Di Cristanziano V, Heger E, Pflieger E, Wyen C, Bettin D, Rybniker J, Fätkenheuer G, Lehmann C. Immune response to mRNA-based COVID-19 booster vaccination in people living with HIV. HIV Med 2023. PubMed

Thibeault C, Bardtke L, Vanshylla K, Cristianzano V, Eberhardt KA, Stubbemann P, Hillus D, Tober-Lau P, Mukherjee P, Münn F, Lippert LJ, Helbig ET, Lingscheid T, Steinbeis F, Mittermaier M, Witzenrath M, Zoller T, Klein F, Sander LE, Kurth F. Short- and long-term T cell and antibody responses following Dexamethasone treatment in COVID-19. JCI Insight 2023. PubMed

Eberhardt KA, Jung V, Knops E, Heger E, Wirtz M, Steger G, Kaiser R, Affeldt P, Holtick U, Klein F, Scheid C, Di Cristanziano V. CMV-IgG pre-allogeneic hematopoietic stem cell transplantation and the risk for CMV reactivation and mortality. Bone Marrow Transplant 2023. PubMed

Skelin J, Đukić A, Filić V, Hufbauer M, Akgül B, Thomas M, Banks L, Tomaić V. MAML1-induced HPV E6 oncoprotein stability is required for cellular proliferation and migration of cervical tumor-derived cells. J Med Virol 2023. PubMed

Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, Hauber I, Hauber J, Heger E, De Clercq J, Vandekerckhove L, Bergmann S, Dunay GA, Klein F, Häussinger D, Fischer JC, Nachtkamp K, Timm J, Kaiser R, Harrer T, Luedde T, Nijhuis M, Sáez-Cirión A, Schulze Zur Wiesch J, Wensing AMJ, Martinez-Picado J, Kobbe G. In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation. Nat Med 2023; 29(3): 583-7. PubMed

Luxenburger H, Reeg DB, Lang-Meli J, Reinscheid M, Eisner M, Bettinger D, Oberhardt V, Salimi Alizei E, Wild K, Graeser A, Karl V, Sagar, Emmerich F, Klein F, Panning M, Huzly D, Bengsch B, Boettler T, Elling R, Thimme R, Hofmann M, Neumann-Haefelin C. Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients. J Hepatol 2023. PubMed

Henze L, Braun J, Meyer-Arndt L, Jürchott K, Schlotz M, Michel J, Grossegesse M, Mangold M, Dingeldey M, Kruse B, Holenya P, Mages N, Reimer U, Eckey M, Schnatbaum K, Wenschuh H, Timmermann B, Klein F, Nitsche A, Giesecke-Thiel C, Loyal L, Thiel A. Primary ChAdOx1 vaccination does not reactivate pre-existing, cross-reactive immunity. Front Immunol 2023; 14: 1056525. PubMed

Raimondi S, Gandini S, Rubio Quintanares GH, Abecasis A, Lopalco PL, D'Ecclesiis O, Chiocca S, Tomezzoli E, Cutica I, Mazzoni D, Amparo N, Pingarilho M, Carmagnola D, Dellavia C, Zuccotti G, Ronchini C, Bellerba F, Dewald F, Kaiser R, Incardona F. Correction: European Cohorts of patients and schools to Advance Response to Epidemics (EuCARE): a cluster randomised interventional and observational study protocol to investigate the relationship between schools and SARS-CoV-2 infection. BMC Infect Dis 2023; 23(1): 96. PubMed

Oberste M, Schnörch N, Shah-Hosseini K, Asenova T, Dewald F, Lehmann C, Buess M, Fätkenheuer G, Klein F, Rosenberger KD, Kossow A, Neuhann F, Hellmich M. Results of the Cologne Corona Surveillance (CoCoS) study - a cross-sectional study: survey data on risk factors of SARS-CoV-2 infection in adults. BMC Public Health 2023; 23(1): 260. PubMed

Jordans CCE, Vasylyev M, Rae C, Jakobsen ML, Vassilenko A, Dauby N, Grevsen AL, Jakobsen SF, Raahauge A, Champenois K, Papot E, Malin JJ, Boender TS, Behrens GMN, Gruell H, Neumann A, Spinner CD, Valbert F, Akinosoglou K, Kostaki EG, Nozza S, Giacomelli A, Lapadula G, Mazzitelli M, Torti C, Matulionyte R, Matulyte E, Van Welzen BJ, Hensley KS, Thompson M, Ankiersztejn-Bartczak M, Skrzat-Klapaczyńska A, Săndulescu O, Streinu-Cercel A, Streinu-Cercel A, Miron VD, Pokrovskaya A, Hachfeld A, Dorokhina A, Sukach M, Lord E, Sullivan AK, Rokx C. National medical specialty guidelines of HIV indicator conditions in Europe lack adequate HIV testing recommendations: a systematic guideline review. Euro Surveill 2022; 27(48). PubMed

Raimondi S, Gandini S, Rubio Quintanares GH, Abecasis A, Lopalco PL, D'Ecclesiis O, Chiocca S, Tomezzoli E, Cutica I, Mazzoni D, Amparo N, Pingarilho M, Carmagnola D, Dellavia C, Zuccotti G, Ronchini C, Bellerba F, Dewald F, Kaiser R, Incardona F. European Cohorts of patients and schools to Advance Response to Epidemics (EuCARE): a cluster randomised interventional and observational study protocol to investigate the relationship between schools and SARS-CoV-2 infection. BMC Infect Dis 2023; 23(1): 1. PubMed

Hufbauer M, Rattay S, Hagen C, Quaas A, Pfister H, Hartmann G, Coch C, Akgül B. Poly(I:C) Treatment Prevents Skin Tumor Formation in the Preclinical HPV8 Transgenic Mouse Model. J Invest Dermatol 2022. PubMed

Pirkl M, Büch J, Devaux C, Böhm M, Sönnerborg A, Incardona F, Abecasis A, Vandamme AM, Zazzi M, Kaiser R, Lengauer T, The EuResist Network Study G. Analysis of mutational history of multidrug-resistant genotypes with a mutagenetic tree model. J Med Virol 2023; 95(1): e28389. PubMed

Kreuter A, Heger E, Wieland U. Monkeypox infection with rapidly developing painful lymphangitis. Int J Dermatol 2023; 62(3): e122-e4. PubMed

Stahl D, Esser RL, Brück C, Thiele J, Di Cristanziano V, Pesch CT, Kofler DM. High increase in levels of lipoprotein(a) in plasma of patients with rheumatoid arthritis after COVID-19. Arthritis Rheumatol 2023; 75(2): 329-31. PubMed

Gliga S, Lübke N, Killer A, Gruell H, Walker A, Dilthey AT, Thielen A, Lohr C, Flaßhove C, Krieg S, Pereira JV, Seraphin TP, Zaufel A, Däumer M, Orth HM, Feldt T, Bode JG, Klein F, Timm J, Luedde T, Jensen BO. Rapid Selection of Sotrovimab Escape Variants in Severe Acute Respiratory Syndrome Coronavirus 2 Omicron-Infected Immunocompromised Patients. Clin Infect Dis 2023; 76(3): 408-15. PubMed

Elvstam O, Malmborn K, Elén S, Marrone G, García F, Zazzi M, Sönnerborg A, Böhm M, Seguin-Devaux C, Björkman P. Virologic Failure Following Low-level Viremia and Viral Blips During Antiretroviral Therapy: Results From a European Multicenter Cohort. Clin Infect Dis 2023; 76(1): 25-31. PubMed

Kreuter A, Grossmann M, Müller VL, Michalowitz AL, Oellig F, Silling S, Heger E, Wieland U. Monkeypox infection with concomitant penile lymphoedema. J Eur Acad Dermatol Venereol 2023; 37(3): e431-e2. PubMed

Kretschmer AC, Junker L, Dewald F, Linne V, Hennen L, Horemheb-Rubio G, Kaiser R, Steger G, Joachim A, Schönenkorb J, Cosgun ZC, Mühlhans N, Heger E, Knops E, Leisse C, Kessel B, Heinsohn T, Rodiah I, Lange B, Ritter AL, Fries M, Kossow A, Nießen J, Dötsch J, Klein F, Rybniker J, Fätkenheuer G, Suárez I. Implementing the Lolli-Method and pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools: a pilot project. Infection 2023; 51(2): 459-64. PubMed

Mansour S, Josephs KS, Ostergaard P, Gordon K, Van Zanten M, Pearce J, Jeffery S, Keeley V, Riches K, Kreuter A, Wieland U, Hägerling R, Ratnam L, Sackey E, Grigoriadis D, Ho B, Smith F, Rauter E, Mortimer P, Macallan D. Redefining WILD syndrome: a primary lymphatic dysplasia with congenital multisegmental lymphoedema, cutaneous lymphovascular malformation, CD4 lymphopaenia and warts. J Med Genet 2023; 60(1): 84-90. PubMed

2022

Jordans CCE, Vasylyev M, Rae C, Jakobsen ML, Vassilenko A, Dauby N, Grevsen AL, Jakobsen SF, Raahauge A, Champenois K, Papot E, Malin JJ, Boender TS, Behrens GMN, Gruell H, Neumann A, Spinner CD, Valbert F, Akinosoglou K, Kostaki EG, Nozza S, Giacomelli A, Lapadula G, Mazzitelli M, Torti C, Matulionyte R, Matulyte E, Van Welzen BJ, Hensley KS, Thompson M, Ankiersztejn-Bartczak M, Skrzat-Klapaczyńska A, Săndulescu O, Streinu-Cercel A, Streinu-Cercel A, Miron VD, Pokrovskaya A, Hachfeld A, Dorokhina A, Sukach M, Lord E, Sullivan AK, Rokx C. National medical specialty guidelines of HIV indicator conditions in Europe lack adequate HIV testing recommendations: a systematic guideline review. Euro Surveill 2022; 27(48). PubMed

Affeldt P, Koehler FC, Brensing KA, Gies M, Platen E, Adam V, Butt L, Grundmann F, Heger E, Hinrichs S, Kalisch N, Oehm S, Steger G, Wirtz M, Benzing T, Stippel D, Klein F, Kurschat C, Müller RU, Di Cristanziano V. Immune Response to Third and Fourth COVID-19 Vaccination in Hemodialysis Patients and Kidney Transplant Recipients. Viruses 2022; 14(12). PubMed

Silling S, Kreuter A, Gambichler T, Meyer T, Stockfleth E, Wieland U. Epidemiology of Merkel Cell Polyomavirus Infection and Merkel Cell Carcinoma. Cancers (Basel) 2022; 14(24). PubMed

Oette M, Corpora S, Laudenberg M, Bewermeier F, Kaiser R, Klein F, Heger E. COVID-19 and Homelessness: Low Vaccination Rate, High Prevalence. Dtsch Arztebl Int 2022; 119(35-36): 603-4. PubMed

Stich M, Di Cristanziano V, Tönshoff B, Weber LT, Dötsch J, Rammer MT, Rieger S, Heger E, Garbade SF, Burgmaier K, Benning L, Speer C, Habbig S, Haumann S. Humoral immune response and live-virus neutralization of the SARS-CoV-2 omicron (BA.1) variant after COVID-19 mRNA vaccination in children and young adults with chronic kidney disease. Pediatr Nephrol 2022: 1-14. PubMed

Braun SA, Bauer AT, Németh C, Rózsa A, Rusch L, Erpenbeck L, Schloer S, Silling S, Metze D, Gerber PA, Schneider SW, Gyulai R, Homey B. Immunothrombotic Mechanisms Induced by Ingenol Mebutate Lead to Rapid Necrosis and Clearance of Anogenital Warts. Int J Mol Sci 2022; 23(21): 13377. PubMed

van de Klundert MAA, Antonova A, Di Teodoro G, Ceña Diez R, Chkhartishvili N, Heger E, Kuznetsova A, Lebedev A, Narayanan A, Ozhmegova E, Pronin A, Shemshura A, Tumanov A, Pfeifer N, Kaiser R, Saladini F, Zazzi M, Incardona F, Bobkova M, Sönnerborg A. Molecular Epidemiology of HIV-1 in Eastern Europe and Russia. Viruses 2022; 14(10): 2099. PubMed

Habermann E, Gieselmann L, Tober-Lau P, Klotsche J, Albach FN, Ten Hagen A, Zernicke J, Ahmadov E, Arumahandi de Silva AN, Frommert LM, Kurth F, Sander LE, Burmester GR, Klein F, Biesen R. Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination. RMD Open 2022; 8(2): e002639. PubMed

Tamura Y, Yamane K, Kawano Y, Bullinger L, Wirtz T, Weber T, Sander S, Ohki S, Kitajima Y, Okada S, Rajewsky K, Yasuda T. Concomitant Cytotoxic Effector Differentiation of CD4(+) and CD8(+) T Cells in Response to EBV-Infected B Cells. Cancers (Basel) 2022; 14(17): 4118. PubMed

Kreuter A, Wieland U. Prevention of Anal Cancer. N Engl J Med 2022; 387(7): 665-6. PubMed

Moran-Tovar R, Gruell H, Klein F, Laessig M. Stochasticity of infectious outbreaks and consequences for optimal interventions. J Phys A Math Theor. 55: 384008 Link

Hirsch C, Park YS, Piechotta V, Chai KL, Estcourt LJ, Monsef I, Salomon S, Wood EM, So-Osman C, McQuilten Z, Spinner CD, Malin JJ, Stegemann M, Skoetz N, Kreuzberger N. SARS-CoV-2-neutralising monoclonal antibodies to prevent COVID-19. Cochrane Database Syst Rev 2022; 6(6): Cd014945. PubMed

Tober-Lau P, Gruell H, Vanshylla K, Koch WM, Hillus D, Schommers P, Suárez I, Suttorp N, Sander LE, Klein F, Kurth F. Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections. Emerg Infect Dis 2022; 28(5): 1050-2. PubMed

Lentzsch AM, Dooling V, Wegner I, Di Cristanziano V, Sadda SR, Freund KB, Liakopoulos S. Acute Exudative Polymorphous Vitelliform Maculopathy Associated With Primary Epstein-Barr Virus Infection. Retin Cases Brief Rep 2022; 16(6): 740-6. PubMed

Dam KA, Barnes CO, Gristick HB, Schoofs T, Gnanapragasam PNP, Nussenzweig MC, Bjorkman PJ. HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun 2022; 13(1): 6123. PubMed

Stahl D, Tho Pesch C, Brück C, Esser RL, Thiele J, Di Cristanziano V, Kofler DM. Reduced humoral response to a third dose (booster) of SARS-CoV-2 mRNA vaccines by concomitant methotrexate therapy in elderly patients with rheumatoid arthritis. RMD Open 2022; 8(2): e002632. PubMed

LaMont C, Otwinowski J, Vanshylla K, Gruell H, Klein F, Nourmohammad A. Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1. Elife 2022; 11: e76004. PubMed

Sharma SJ, Schartinger VH, Wuerdemann N, Langer C, Möllenhoff K, Collin L, Sutton L, Riedl D, Kreuter A, Lechner M, Wieland U, Klussmann JP. Awareness of Human Papillomavirus (HPV) and HPV Vaccination amongst the General Population in Germany: Lack of Awareness and Need for Action. Oncol Res Treat 2022; 45(10): 561-7. PubMed

Mellinghoff SC, Mayer L, Robrecht S, Weskamm LM, Dahlke C, Gruell H, Schlotz M, Vanshylla K, Schloser HA, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Eichhorst B, Hallek M, Langerbeins P. SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia. Haematologica 2022; 107(10): 2480-4. PubMed

Gruell H, Vanshylla K, Tober-Lau P, Hillus D, Sander LE, Kurth F, Klein F. Neutralisation sensitivity of the SARS-CoV-2 omicron BA.2.75 sublineage. Lancet Infect Dis 2022; 22(10): 1422-3. PubMed

Barnes CO, Schoofs T, Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H, Schommers P, Suh-Toma N, Lee YE, Cetrulo Lorenzi JC, Piechocka-Trocha A, Scheid JF, West AP, Jr., Walker BD, Seaman MS, Klein F, Nussenzweig MC, Bjorkman PJ. A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv 2022; 8(32): eabp8155. PubMed

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Gruell H, Vanshylla K, Korenkov M, Tober-Lau P, Zehner M, Münn F, Janicki H, Augustin M, Schommers P, Sander LE, Kurth F, Kreer C, Klein F. SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns. Cell Host Microbe 2022; 30(9): 1231-41.e6. PubMed

Dewald F, Detmer S, Pirkl M, Hellmich M, Heger E, Herrmann M, Zweigner J, Klein F. Viral load dynamics in SARS-CoV-2 Omicron breakthrough infections. J Infect Dis 2022; 226(10): 1721-5. PubMed

Meyer M, Ruebsteck E, Dewald F, Klein F, Lehmann C, Huenseler C, Weber LT. Clinical Aspects of the Subsequent SARS-CoV-2 Waves in Children from 2020 to 2022-Data from a Local Cohort in Cologne, Germany (n = 21,635). Viruses 2022; 14(8): 1607. PubMed

Feles S, Overath C, Reichardt S, Diegeler S, Schmitz C, Kronenberg J, Baumstark-Khan C, Hemmersbach R, Hellweg CE, Liemersdorf C. Streamlining Culture Conditions for the Neuroblastoma Cell Line SH-SY5Y: A Prerequisite for Functional Studies. Methods Protoc 2022; 5(4): 58. PubMed

Rattay S, Hufbauer M, Hagen C, Putschli B, Coch C, Akgül B, Hartmann G. Human Beta Papillomavirus Type 8 E1 and E2 Proteins Suppress the Activation of the RIG-I-Like Receptor MDA5. Viruses 2022; 14(7): 1361. PubMed

Sarfo FS, Dompreh A, Asibey SO, Boateng R, Weinreich F, Kuffour EO, Norman B, Di Cristanziano V, Frickmann H, Feldt T, Eberhardt KA. The Clinical Features and Immunological Signature of Cyclospora cayetanensis Co-Infection among People Living with HIV in Ghana. Microorganisms 2022; 10(7): 1407. PubMed

Weinreich F, Hahn A, Eberhardt KA, Kann S, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Comparative Evaluation of Real-Time Screening PCR Assays for Giardia duodenalis and of Assays Discriminating the Assemblages A and B. Microorganisms 2022; 10(7): 1310. PubMed

Oberste M, Pusch LM, Roth R, Shah-Hosseini K, Schmitz J, Heger E, Dewald F, Müller C, von Goltzheim LS, Lehmann C, Buess M, Wolff A, Fätkenheuer G, Wiesmüller G, Klein F, Rosenberger KD, Neuhann F, Hellmich M. Results of the Cologne Corona surveillance (CoCoS) study - a prospective population-based cohort study: incidence data and potential underestimation of new SARS-CoV-2 adult infections by health authorities. BMC Public Health 2022; 22(1): 1379. PubMed

Chiapponi C, Faust M, Schmidt M, Thomas M, Schultheis AM, Akgul B, Alakus H. Subacute thyroiditis after SARS-Cov2 vaccination: A review of the cases being described and personal experience. Endocr Regul 2022; 56(3): 227-31. PubMed

Svačina MKR, Meißner A, Schweitzer F, Ladwig A, Sprenger-Svačina A, Klein I, Wüstenberg H, Kohle F, Schneider C, Grether NB, Wunderlich G, Fink GR, Klein F, Di Cristanziano V, Lehmann HC. Antibody response after COVID-19 vaccination in intravenous immunoglobulin-treated immune neuropathies. Eur J Neurol 2022; 29(11): 3380-8. PubMed 

Meyer-Arndt L, Braun J, Fauchere F, Vanshylla K, Loyal L, Henze L, Kruse B, Dingeldey M, Jürchott K, Mangold M, Maraj A, Braginets A, Böttcher C, Nitsche A, de la Rosa K, Ratswohl C, Sawitzki B, Holenya P, Reimer U, Sander LE, Klein F, Paul F, Bellmann-Strobl J, Thiel A, Giesecke-Thiel C. SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod. J Neurol Neurosurg Psychiatry 2022; 93(9): 960-71. PubMed

Kretschmer AC, Junker L, Dewald F, Linne V, Hennen L, Horemheb-Rubio G, Kaiser R, Steger G, Joachim A, Schönenkorb J, Cosgun ZC, Mühlhans N, Heger E, Knops E, Leisse C, Kessel B, Heinsohn T, Rodiah I, Lange B, Ritter AL, Fries M, Kossow A, Nießen J, Dötsch J, Klein F, Rybniker J, Fätkenheuer G, Suárez I. Implementing the Lolli-Method and pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools: a pilot project. Infection 2022: 1-6. PubMed

Koehler FC, Di Cristanziano V, Späth MR, Hoyer-Allo KJR, Wanken M, Müller RU, Burst V. The kidney in hantavirus infection-epidemiology, virology, pathophysiology, clinical presentation, diagnosis and management. Clin Kidney J 2022; 15(7): 1231-52. PubMed

Dewald F, Suárez I, Johnen R, Grossbach J, Moran-Tovar R, Steger G, Joachim A, Rubio GH, Fries M, Behr F, Kley J, Lingnau A, Kretschmer A, Gude C, Baeza-Flores G, Del Valle DL, Roblero-Hernandez A, Magana-Cerino J, Hernandez AT, Ruiz-Quinones J, Schega K, Linne V, Junker L, Wunsch M, Heger E, Knops E, Di Cristanziano V, Meyer M, Hünseler C, Weber LT, Lüers JC, Quade G, Wisplinghoff H, Tiemann C, Zotz R, Jomaa H, Pranada A, Herzum I, Cullen P, Schmitz FJ, Philipsen P, Kirchner G, Knabbe C, Hellmich M, Buess M, Wolff A, Kossow A, Niessen J, Jeworutzki S, Schräpler JP, Lässig M, Dötsch J, Fätkenheuer G, Kaiser R, Beyer A, Rybniker J, Klein F. Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children. Nat Commun 2022; 13(1): 3640. PubMed

Horemheb-Rubio G, Eggeling R, Schmeiβer N, Pfeifer N, Lengauer T, Gärtner BC, Prifert C, Kochanek M, Scheid C, Adams O, Kaiser R. Respiratory viruses dynamics and interactions: ten years of surveillance in central Europe. BMC Public Health 2022; 22(1): 1167. PubMed 

Rhee SY, Boehm M, Tarasova O, Di Teodoro G, Abecasis AB, Sönnerborg A, Bailey AJ, Kireev D, Zazzi M, The EuResist Network Study G, Shafer RW. Spectrum of Atazanavir-Selected Protease Inhibitor-Resistance Mutations. Pathogens 2022; 11(5): 546. PubMed

Gruell H, Vanshylla K, Weber T, Barnes CO, Kreer C, Klein F. Antibody-mediated neutralization of SARS-CoV-2. Immunity 2022; 55(6): 925-44. PubMed

Gruell H, Gunst JD, Cohen YZ, Pahus MH, Malin JJ, Platten M, Millard KG, Tolstrup M, Jones RB, Conce Alberto WD, Lorenzi JCC, Oliveira TY, Kümmerle T, Suárez I, Unson-O’Brien C, Nogueira L, Olesen R, Østergaard L, Nielsen H, Lehmann C, Nussenzweig MC, Fätkenheuer G, Klein F, Caskey M, Søgaard OS. Effect of 3BNC117 and romidepsin on the HIV-1 reservoir in people taking suppressive antiretroviral therapy (ROADMAP): a randomised, open-label, phase 2A trial. Lancet Microbe 2022; 3(3): e203-e14. PubMed

Miranda MNS, Pingarilho M, Pimentel V, Martins M, Kaiser R, Seguin-Devaux C, Paredes R, Zazzi M, Incardona F, Abecasis AB. Trends of Transmitted and Acquired Drug Resistance in Europe From 1981 to 2019: A Comparison Between the Populations of Late Presenters and Non-late Presenters. Front Microbiol 2022; 13: 846943. PubMed

Silling S, Kreuter A, Wieland U. [Human polyomavirus-associated skin diseases]. Hautarzt 2022; 73(6): 426-33. PubMed

Hasche D, Akgül B. [Role of human papillomavirus (HPV) in the development of skin cancer]. Hautarzt 2022; 73(6): 417-25. PubMed

Augustin M, Horn C, Ercanoglu MS, Sandaradura de Silva U, Bondet V, Suarez I, Chon SH, Nierhoff D, Knops E, Heger E, Vivaldi C, Schäfer H, Oette M, Fätkenheuer G, Klein F, Duffy D, Müller-Trutwin M, Lehmann C. CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue. Pathogens 2022; 11(4): 483. PubMed

Stemler J, Kramer T, Dimitriou V, Wieland U, Schumacher S, Sprute R, Oberste M, Wiesmüller G, Rau H, Pieper S, Bethe U, Lehmann C, Hellmich M, Klein F, Langebartels G, Cornely OA. Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study. Infection 2022; 50(3): 607-16. PubMed

Syed AS, Marcuzzi GP, Miller-Lazic D, Hess J, Hufbauer M, Akgül B. HPV8 Reverses the Transcriptional Output in Lrig1 Positive Cells to Drive Skin Tumorigenesis. Cancers (Basel) 2022; 14(7): 1662. PubMed

Donmez HG, Akgor U, Onder S, Tanacan A, Kuru O, Ozgul N, Usubutun A, Hufbauer M, Akgül B, Beksac MS. Impact of Human Papillomavirus on Wnt/Beta-Catenin Signaling in Morphological Inconspicuous Cervicovaginal Cells. Acta Cytol 2022; 66(5): 409-19. PubMed

Gruell H, Schommers P. Broadly neutralizing antibodies against HIV-1 and concepts for application. Curr Opin Virol 2022; 54: 101211. PubMed

Poopalasingam N, Korenkov M, Ashurov A, Strobel J, Fish I, Hellmich M, Gruell H, Lehmann C, Heger E, Klein F. Determining the reliability of rapid SARS-CoV-2 antigen detection in fully vaccinated individuals. J Clin Virol 2022; 148: 105119. PubMed

Vanshylla K, Tober-Lau P, Gruell H, Münn F, Eggeling R, Pfeifer N, Le NH, Landgraf I, Kurth F, Sander LE, Klein F. Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults. Lancet Infect Dis 2022; 22(4): 445-6. PubMed

Habermann D, Kharimzadeh H, Walker A, Li Y, Yang R, Kaiser R, Brumme ZL, Timm J, Roggendorf M, Hoffmann D. HAMdetector: A Bayesian regression model that integrates information to detect HLA-associated mutations. Bioinformatics 2022; 38(9): 2428-36. PubMed

Ercanoglu MS, Gieselmann L, Dähling S, Poopalasingam N, Detmer S, Koch M, Korenkov M, Halwe S, Klüver M, Di Cristanziano V, Janicki H, Schlotz M, Worczinski J, Gathof B, Gruell H, Zehner M, Becker S, Vanshylla K, Kreer C, Klein F. No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults. iScience 2022; 25(3): 103951. PubMed

Tanida K, Hahn A, Eberhardt KA, Tannich E, Landt O, Kann S, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Correction: Tanida et al. Comparative Assessment of In-House Real-Time PCRs Targeting Enteric Disease-Associated Microsporidia in Human Stool Samples. Pathogens 2021, 10, 656. Pathogens 2022; 11(2): 256. PubMed

Weinreich F, Hahn A, Eberhardt KA, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Comparison of Three Real-Time PCR Assays for the Detection of Cyclospora cayetanensis in Stool Samples Targeting the 18S rRNA Gene and the hsp70 Gene. Pathogens 2022; 11(2): 165. PubMed

Meyer M, Ruebsteck E, Eifinger F, Klein F, Oberthuer A, Van-Koningsbruggen-Rietschel S, Huenseler C, Weber LT. Morbidity of Respiratory Syncytial Virus-infections (RSV): RSV compared with SARS-CoV-2 infections in children aged 0 - 4 years in Cologne, Germany. J Infect Dis 2022; 226(12): 2050-3. PubMed

Popping S, Cento V, Seguin-Devaux C, Boucher CAB, de Salazar A, Heger E, Mor O, Sayan M, Salmon-Ceron D, Weis N, Krarup HB, de Knegt RJ, Săndulescu O, Chulanov V, van de Vijver D, García F, Ceccherini-Silberstein F. The European Prevalence of Resistance Associated Substitutions among Direct Acting Antiviral Failures. Viruses 2021; 14(1). PubMed

Affeldt P, Koehler FC, Brensing KA, Adam V, Burian J, Butt L, Gies M, Grundmann F, Hinrichs S, Johannis W, Kalisch N, Meyer-Delpho M, Oehm S, Platen E, Schöler C, Heger E, Steger G, Stippel D, Ziegelhöfer A, Benzing T, Klein F, Kurschat C, Müller RU, Cristanziano VD. Immune Responses to SARS-CoV-2 Infection and Vaccination in Dialysis Patients and Kidney Transplant Recipients. Microorganisms 2021; 10(1). PubMed

Beste NC, Davis X, Kloeckner R, Celik E, Korenkov M, Maintz D, Dratsch T, Pinto Dos Santos D. Comprehensive analysis of Twitter usage during a major medical conference held virtually versus in-person. Insights Imaging 2022; 13(1): 8. PubMed

Gruell H, Vanshylla K, Tober-Lau P, Hillus D, Schommers P, Lehmann C, Kurth F, Sander LE, Klein F. mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant. Nat Med 2022; 28(3): 477-80. PubMed

Kochanek M, Garcia Borrega J, Beckmann L, Neuhann J, Gathof BS, Di Cristanziano V, Hagmann H, Borrega G. Plasma exchange with COVID-19 convalescent plasma in a patient with severe ANCA-associated vasculitis and COVID-19 pneumonia after rituximab therapy. Clin Kidney J 2022; 15(1): 162-4. PubMed

Domröse CM, Wieland U, Pilch H, Einzmann T, Schömig-Markiefka B, Mallmann P, Silling S, Mallmann MR. Cervical Intraepithelial Neoplasia 3 (Cervical Intraepithelial Neoplasia 3/High-Grade Squamous Intraepithelial Lesion) in Human Papillomavirus-Vaccinated Women-Results From a Tertiary Referral Center. J Low Genit Tract Dis 2022; 26(2): 122-6. PubMed

Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity 2022; 55(2): 341-54.e7. PubMed

Vanshylla K, Fan C, Wunsch M, Poopalasingam N, Meijers M, Kreer C, Kleipass F, Ruchnewitz D, Ercanoglu MS, Gruell H, Münn F, Pohl K, Janicki H, Nolden T, Bartl S, Stein SC, Augustin M, Dewald F, Gieselmann L, Schommers P, Schulz TF, Sander LE, Koch M, Łuksza M, Lässig M, Bjorkman PJ, Klein F. Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers. Cell Host Microbe 2022; 30(1): 69-82.e10. PubMed

Mellinghoff SC, Robrecht S, Mayer L, Weskamm LM, Dahlke C, Gruell H, Vanshylla K, Schlösser HA, Thelen M, Fink AM, Fischer K, Klein F, Addo MM, Eichhorst B, Hallek M, Langerbeins P. SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia. Leukemia 2022; 36(2): 562-5. PubMed

Malin JJ, Di Cristanziano V, Horn C, Pracht E, Garcia Borrega J, Heger E, Knops E, Kaiser R, Böll B, Lehmann C, Jung N, Borchmann P, Fätkenheuer G, Klein F, Hallek M, Rybniker J. SARS-CoV-2-neutralizing antibody treatment in patients with COVID-19 and immunodeficiency due to B-cell non-Hodgkin lymphoma. Blood Adv 2022; 6(5): 1580-4. PubMed

Kreuter A, Wieland U. New important data on the transmission of cutaneous human papillomaviruses. J Eur Acad Dermatol Venereol 2022; 36(1): 11-2. PubMed

Lentzen MP, Huebenthal V, Kaiser R, Kreppel M, Zoeller JE, Zirk M. A retrospective analysis of social media posts pertaining to COVID-19 vaccination side effects. Vaccine 2022; 40(1): 43-51. PubMed

Schweitzer F, Goereci Y, Franke C, Silling S, Bösl F, Maier F, Heger E, Deiman B, Prüss H, Onur OA, Klein F, Fink GR, Di Cristanziano V, Warnke C. Cerebrospinal Fluid Analysis Post-COVID-19 Is Not Suggestive of Persistent Central Nervous System Infection. Ann Neurol 2022; 91(1): 150-7. PubMed

Tufa TB, Fuchs A, Orth HM, Lübke N, Knops E, Heger E, Jarso G, Hurissa Z, Eggers Y, Häussinger D, Luedde T, Jensen BO, Kaiser R, Feldt T. Characterization of HIV-1 drug resistance among patients with failure of second-line combined antiretroviral therapy in central Ethiopia. HIV Med 2022; 23(2): 159-68. PubMed

2021

Wagh K, van Gils MJ, Gristick H, Schommers P. Editorial: Novel Concepts in Using Broadly Neutralizing Antibodies for HIV-1 Treatment and Prevention. Front Immunol 2021; 12: 823576. PubMed

Mellinghoff SC, Vanshylla K, Dahlke C, Addo MM, Cornely OA, Klein F, Persigehl T, Rybniker J, Gruell H, Bröckelmann PJ. Case Report: Clinical Management of a Patient With Metastatic Non-Small Cell Lung Cancer Newly Receiving Immune Checkpoint Inhibition During Symptomatic COVID-19. Front Immunol 2021; 12: 798276. PubMed

Köksal MO, Yalçın BK, Keskin F, Çiftçi S, Yağcı I, Hasçiçek S, Başaran B, Değer K, Ağaçfidan A, Quaas A, Akgül B. Genotype Distribution and Prevalence of Human Papillomavirus in Head and Neck Cancer Samples from Istanbul, Turkey. Pathogens 2021; 10(12). PubMed

Oette M, Corpora S, Baron M, Laudenberg M, Kaiser R, Klein F, Heger E. The Prevalence of SARS-CoV-2 Infection Among Homeless Persons in Cologne, Germany. Dtsch Arztebl Int 2021; 118(40): 678-9. PubMed

Mansour S, Josephs KS, Ostergaard P, Gordon K, Van Zanten M, Pearce J, Jeffery S, Keeley V, Riches K, Kreuter A, Wieland U, Hägerling R, Ratnam L, Sackey E, Grigoriadis D, Ho B, Smith F, Rauter E, Mortimer P, Macallan D. Redefining WILD syndrome: a primary lymphatic dysplasia with congenital multisegmental lymphoedema, cutaneous lymphovascular malformation, CD4 lymphopaenia and warts. J Med Genet 2021. PubMed

Hufbauer M, Wieland U, Gebel J, Steinmann J, Akgül B, Eggers M. Inactivation of Polyomavirus SV40 as Surrogate for Human Papillomaviruses by Chemical Disinfectants. Viruses 2021; 13(11). PubMed

Wunsch M, Aschemeier D, Heger E, Ehrentraut D, Krüger J, Hufbauer M, Syed AS, Horemheb-Rubio G, Dewald F, Fish I, Schlotz M, Gruell H, Augustin M, Lehmann C, Kaiser R, Knops E, Silling S, Klein F. Safe and effective pool testing for SARS-CoV-2 detection. J Clin Virol 2021; 145: 105018. PubMed

Koehler FC, Blomberg L, Brehm TT, Büttner S, Cornely OA, Degen O, Di Cristanziano V, Dolff S, Eberwein L, Hoxha E, Hoyer-Allo KJR, Rudolf S, Späth MR, Wanken M, Müller RU, Burst V. Development and design of the Hantavirus registry - HantaReg - for epidemiological studies, outbreaks and clinical studies on hantavirus disease. Clin Kidney J 2021; 14(11): 2365-70. PubMed

Bopp L, Wieland U, Hellmich M, Kreuter A, Pfister H, Silling S. Natural History of Cutaneous Human Polyomavirus Infection in Healthy Individuals. Front Microbiol 2021; 12: 740947. PubMed

Müller L, Andrée M, Ostermann PN, Jazmati N, Flüh G, Fischer JC, Bölke E, Heger E, Vanshylla K, Klein F, Wisplinghoff H, Schaal H, Drexler I, Walker A, Adams O, Timm J. SARS-CoV-2 Infection in Fully Vaccinated Individuals of Old Age Strongly Boosts the Humoral Immune Response. Front Med (Lausanne) 2021; 8: 746644. PubMed

Tober-Lau P, Schwarz T, Vanshylla K, Hillus D, Gruell H, Suttorp N, Landgraf I, Kappert K, Seybold J, Drosten C, Klein F, Kurth F, Sander LE, Corman VM. Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers. Lancet Respir Med 2021; 9(11): e104-e5. PubMed

Uzun S, Korkmaz Y, Wuerdemann N, Arolt C, Puladi B, Siefer OG, Dönmez HG, Hufbauer M, Akgül B, Klussmann JP, Huebbers CU. Comprehensive Analysis of VEGFR2 Expression in HPV-Positive and -Negative OPSCC Reveals Differing VEGFR2 Expression Patterns. Cancers (Basel) 2021; 13(20). PubMed

Stemler J, Kramer T, Dimitriou V, Wieland U, Schumacher S, Sprute R, Oberste M, Wiesmüller G, Rau H, Pieper S, Bethe U, Lehmann C, Hellmich M, Klein F, Langebartels G, Cornely OA. Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study. Infection 2021: 1-10. PubMed

Weinreich F, Hahn A, Eberhardt KA, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis of Cryptosporidium spp. in Stool Samples. Pathogens 2021; 10(9). PubMed

Garcia Borrega J, Naendrup JH, Heindel K, Hamacher L, Heger E, Di Cristanziano V, Deppe AC, Dusse F, Wetsch WA, Eichenauer DA, Shimabukuro-Vornhagen A, Böll B, Kochanek M. Clinical Course and Outcome of Patients with SARS-CoV-2 Alpha Variant Infection Compared to Patients with SARS-CoV-2 Wild-Type Infection Admitted to the ICU. Microorganisms 2021; 9(9). PubMed

Kirschberg M, Syed AS, Dönmez HG, Heuser S, Wilbrand-Hennes A, Alonso A, Hufbauer M, Akgül B. Novel Insights Into Cellular Changes in HPV8-E7 Positive Keratinocytes: A Transcriptomic and Proteomic Analysis. Front Microbiol 2021; 12: 672201. PubMed

Köksal MO, Akgül B, Beka H, Çiftçi S, Keskin F, Eraksoy H, Ağaçfidan A. Frequency of CCR5-Δ32, CCR2-64I and SDF1-3'A alleles in HIV-infected and uninfected patients in Istanbul, Turkey. J Infect Dev Ctries 2021; 15(8): 1183-9. PubMed

Kreuzberger N, Hirsch C, Chai KL, Tomlinson E, Khosravi Z, Popp M, Neidhardt M, Piechotta V, Salomon S, Valk SJ, Monsef I, Schmaderer C, Wood EM, So-Osman C, Roberts DJ, McQuilten Z, Estcourt LJ, Skoetz N. SARS-CoV-2-neutralising monoclonal antibodies for treatment of COVID-19. Cochrane Database Syst Rev 2021; 9(9): Cd013825. PubMed

Joachim A, Dewald F, Suárez I, Zemlin M, Lang I, Stutz R, Marthaler A, Bosse HM, Lübke N, Münch J, Bernard MA, Jeltsch K, Tönshoff B, Weidner N, Kräusslich HG, Birzele L, Hübner J, Schmied P, Meyer-Bühn M, Horemheb-Rubio G, Cornely OA, Haverkamp H, Wiesmüller G, Fätkenheuer G, Hero B, Kaiser R, Dötsch J, Rybniker J. Pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools - a cluster randomised trial. EClinicalMedicine 2021; 39: 101082. PubMed

Meyer M, Holfter A, Ruebsteck E, Gruell H, Dewald F, Koerner RW, Klein F, Lehmann C, Huenseler C, Weber LT. The Alpha Variant (B.1.1.7) of SARS-CoV-2 in Children: First Experience from 3544 Nucleic Acid Amplification Tests in a Cohort of Children in Germany. Viruses 2021; 13(8). PubMed

Halwe S, Kupke A, Vanshylla K, Liberta F, Gruell H, Zehner M, Rohde C, Krähling V, Gellhorn Serra M, Kreer C, Klüver M, Sauerhering L, Schmidt J, Cai Z, Han F, Young D, Yang G, Widera M, Koch M, Werner A, Kämper L, Becker N, Marlow MS, Eickmann M, Ciesek S, Schiele F, Klein F, Becker S. Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Viruses 2021; 13(8). PubMed

Blohm M, Hahn A, Hagen RM, Eberhardt KA, Rohde H, Leboulle G, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Comparison of Two Real-Time PCR Assays Targeting Ribosomal Sequences for the Identification of Cystoisospora belli in Human Stool Samples. Pathogens 2021; 10(8). PubMed

Eberhardt KA, Sarfo FS, Klupp EM, Dompreh A, Di Cristanziano V, Osei Kuffour E, Boateng R, Norman B, Phillips RO, Aepfelbacher M, Feldt T. Intestinal Colonization with Tropheryma whipplei-Clinical and Immunological Implications for HIV Positive Adults in Ghana. Microorganisms 2021; 9(8). PubMed

Di Cristanziano V, Farowski F, Berrilli F, Santoro M, Di Cave D, Glé C, Daeumer M, Thielen A, Wirtz M, Kaiser R, Eberhardt KA, Vehreschild M, D'Alfonso R. Analysis of Human Gut Microbiota Composition Associated to the Presence of Commensal and Pathogen Microorganisms in Côte d'Ivoire. Microorganisms 2021; 9(8). PubMed

Di Cristanziano V, Affeldt P, Trappe M, Wirtz M, Heger E, Knops E, Kaiser R, Stippel D, Müller RU, Holtick U, Scheid C, Kann M, Kurschat CE, Grundmann F. Combined Therapy with Intravenous Immunoglobulins, Letermovir and (Val-)Ganciclovir in Complicated Courses of CMV-Infection in Transplant Recipients. Microorganisms 2021; 9(8). PubMed

Hillus D, Schwarz T, Tober-Lau P, Vanshylla K, Hastor H, Thibeault C, Jentzsch S, Helbig ET, Lippert LJ, Tscheak P, Schmidt ML, Riege J, Solarek A, von Kalle C, Dang-Heine C, Gruell H, Kopankiewicz P, Suttorp N, Drosten C, Bias H, Seybold J, Klein F, Kurth F, Corman VM, Sander LE. Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study. Lancet Respir Med 2021; 9(11): 1255-65. PubMed

Wei F, Gaisa MM, D'Souza G, Xia N, Giuliano AR, Hawes SE, Gao L, Cheng SH, Donà MG, Goldstone SE, Schim van der Loeff MF, Neukam K, Meites E, Poynten IM, Dai J, Combes JD, Wieland U, Burgos J, Wilkin TJ, Hernandez AL, Iribarren Díaz M, Hidalgo-Tenorio C, Valencia Arredondo M, Nyitray AG, Wentzensen N, Chow EP, Smelov V, Nowak RG, Phanuphak N, Woo YL, Choi Y, Hu Y, Schofield AM, Woestenberg PJ, Chikandiwa AT, Hickey AC, de Pokomandy A, Murenzi G, Péré H, Del Pino M, Ortiz AP, Charnot-Katsikas A, Liu X, Chariyalertsak S, Strong C, Ong JJ, Yunihastuti E, Etienney I, Ferré VM, Zou H, Segondy M, Chinyowa S, Alberts CJ, Clifford GM. Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies. Lancet HIV 2021; 8(9): e531-e43. PubMed

Meijers M, Vanshylla K, Gruell H, Klein F, Lässig M. Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody. Proc Natl Acad Sci U S A 2021; 118(30). PubMed

Kreuter A, Silling S, Potthoff A, Oellig F, Michalowitz AL, Wieland U. Human papillomavirus type 67 in cutaneous squamous cell dysplasia and carcinoma. J Eur Acad Dermatol Venereol 2021; 35(11): e807-e9. PubMed

Oberste M, Pusch LM, Roth R, Shah-Hosseini K, Dewald F, Müller C, Stach von Goltzheim L, Lehmann C, Buess M, Wolff A, Fätkenheuer G, Wiesmüller G, Klein F, Hellmich M, Neuhann F. Protocol of the Cologne Corona Surveillance (CoCoS) Study- a prospective population-based cohort study. BMC Public Health 2021; 21(1): 1295. PubMed

Korenkov M, Poopalasingam N, Madler M, Vanshylla K, Eggeling R, Wirtz M, Fish I, Dewald F, Gieselmann L, Lehmann C, Fätkenheuer G, Gruell H, Pfeifer N, Heger E, Klein F. Evaluation of a Rapid Antigen Test To Detect SARS-CoV-2 Infection and Identify Potentially Infectious Individuals. J Clin Microbiol 2021; 59(9): e0089621. PubMed

Reif T, Dyckhoff G, Hohenberger R, Kolbe CC, Gruell H, Klein F, Latz E, Stolp B, Fackler OT. Contact-dependent inhibition of HIV-1 replication in ex vivo human tonsil cultures by polymorphonuclear neutrophils. Cell Rep Med 2021; 2(6): 100317. PubMed

Vigón L, Martínez-Román P, Rodríguez-Mora S, Torres M, Puertas MC, Mateos E, Salgado M, Navarro A, Sánchez-Conde M, Ambrosioni J, Cervero M, Wyen C, Hoffmann C, Miró JM, Alcamí J, Podzamczer D, García-Gutiérrez V, Martínez-Picado J, Briz V, Rosa López-Huertas M, Planelles V, Coiras M. Provirus reactivation is impaired in HIV-1 infected individuals on treatment with dasatinib and antiretroviral therapy. Biochem Pharmacol 2021; 192: 114666. PubMed

Kreuter A, Koushk-Jalali B, Akgül B, Silling S, Oellig F, Has C, Wieland U. HPV-5-associated cutaneous squamous cell carcinoma in situ in poikiloderma with neutropenia. Clin Exp Dermatol 2021; 46(8): 1619-21. PubMed

Wennhold K, Thelen M, Lehmann J, Schran S, Preugszat E, Garcia-Marquez M, Lechner A, Shimabukuro-Vornhagen A, Ercanoglu MS, Klein F, Thangarajah F, Eidt S, Löser H, Bruns C, Quaas A, von Bergwelt-Baildon M, Schlößer HA. CD86(+) Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses. Cancer Immunol Res 2021; 9(9): 1098-108. PubMed

Kitanovski S, Horemheb-Rubio G, Adams O, Gärtner B, Lengauer T, Hoffmann D, Kaiser R. Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2. BMC Public Health 2021; 21(1): 1178. PubMed

Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J. Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med 2021; 13(8): e14150. PubMed

Tanida K, Hahn A, Eberhardt KA, Tannich E, Landt O, Kann S, Feldt T, Sarfo FS, Di Cristanziano V, Frickmann H, Loderstädt U. Comparative Assessment of In-House Real-Time PCRs Targeting Enteric Disease-Associated Microsporidia in Human Stool Samples. Pathogens 2021; 10(6). PubMed

Gambichler T, Abu Rached N, Tannapfel A, Becker JC, Vogt M, Skrygan M, Wieland U, Silling S, Susok L, Stücker M, Meyer T, Stockfleth E, Junker K, Käfferlein HU, Brüning T, Lang K. Expression of Mismatch Repair Proteins in Merkel Cell Carcinoma. Cancers (Basel) 2021; 13(11). PubMed

Gieselmann L, Kreer C, Ercanoglu MS, Lehnen N, Zehner M, Schommers P, Potthoff J, Gruell H, Klein F. Effective high-throughput isolation of fully human antibodies targeting infectious pathogens. Nat Protoc 2021; 16(7): 3639-71. PubMed

Augustin M, Schommers P, Stecher M, Dewald F, Gieselmann L, Gruell H, Horn C, Vanshylla K, Cristanziano VD, Osebold L, Roventa M, Riaz T, Tschernoster N, Altmueller J, Rose L, Salomon S, Priesner V, Luers JC, Albus C, Rosenkranz S, Gathof B, Fätkenheuer G, Hallek M, Klein F, Suárez I, Lehmann C. Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study. Lancet Reg Health Eur 2021; 6: 100122. PubMed

Vanshylla K, Di Cristanziano V, Kleipass F, Dewald F, Schommers P, Gieselmann L, Gruell H, Schlotz M, Ercanoglu MS, Stumpf R, Mayer P, Zehner M, Heger E, Johannis W, Horn C, Suárez I, Jung N, Salomon S, Eberhardt KA, Gathof B, Fätkenheuer G, Pfeifer N, Eggeling R, Augustin M, Lehmann C, Klein F. Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans. Cell Host Microbe 2021; 29(6): 917-29.e4. PubMed

Meyer M, Ruebsteck E, Gruell H, Klein F, Lehmann C, Wendt S, Huenseler C, Weber LT. COVID-19 study found that 0.4% of 5730 asymptomatic children aged 0-18 years tested positive for virus before hospital procedures or admission. Acta Paediatr 2021; 110(9): 2584-5. PubMed

Bamidis AD, Koehler P, di Cristanziano V, Rasche K, Demirel B, Bacher P, Hallek M, Kochanek M, Klein F, Hofmann SC, Wesselmann U, Kofler DM. First manifestation of adult-onset Still's disease after COVID-19. Lancet Rheumatol 2021; 3(5): e319-e21. PubMed

Eberhardt KA, Dewald F, Heger E, Gieselmann L, Vanshylla K, Wirtz M, Kleipass F, Johannis W, Schommers P, Gruell H, Brensing KA, Müller RU, Augustin M, Lehmann C, Koch M, Klein F, Di Cristanziano V. Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG. Microorganisms 2021; 9(4). PubMed

Vanshylla K, Held K, Eser TM, Gruell H, Kleipass F, Stumpf R, Jain K, Weiland D, Münch J, Grüttner B, Geldmacher C, Klein F. CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention. Vaccines (Basel) 2021; 9(3). PubMed

Marty N, Saeng-Aroon S, Heger E, Thielen A, Obermeier M, Pfeifer N, Kaiser R, Klimkait T. Adapting the geno2pheno[coreceptor] tool to HIV-1 subtype CRF01_AE by phenotypic validation using clinical isolates from South-East Asia. J Clin Virol 2021; 136: 104755. PubMed

Gross GE, Werner RN, Avila Valle GL, Bickel M, Brockmeyer NH, Doubek K, Gallwas J, Gieseking F, Haase H, Hillemanns P, Ikenberg H, Jongen J, Kaufmann AM, Klußmann JP, von Knebel Doeberitz M, Knuf M, Köllges R, Laws HJ, Mikolajczyk R, Neis KJ, Petry KU, Pfister H, Schlaeger M, Schneede P, Schneider A, Smola S, Tiews S, Nast A, Gaskins M, Wieland U. German evidence and consensus-based (S3) guideline: Vaccination recommendations for the prevention of HPV-associated lesions. J Dtsch Dermatol Ges 2021; 19(3): 479-94. PubMed

Affeldt P, Di Cristanziano V, Grundmann F, Wirtz M, Kaiser R, Benzing T, Stippel D, Kann M, Kurschat C. Monitoring of hepatitis E virus RNA during treatment for chronic hepatitis E virus infection after renal transplantation. Immun Inflamm Dis 2021; 9(2): 513-20. PubMed

Schmidt L, Jensen BO, Walker A, Keitel-Anselmino V, di Cristanziano V, Böhm M, Knops E, Heger E, Kaiser R, de Luca A, Oette M, Häussinger D, Timm J, Fuchs A, Lübke N. Torque Teno Virus plasma level as novel biomarker of retained immunocompetence in HIV-infected patients. Infection 2021; 49(3): 501-9. PubMed

Müller L, Ostermann PN, Walker A, Wienemann T, Mertens A, Adams O, Andree M, Hauka S, Lübke N, Keitel V, Drexler I, Di Cristanziano V, Hermsen DF, Kaiser R, Boege F, Klein F, Schaal H, Timm J, Senff T. Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting. Eur J Clin Microbiol Infect Dis 2021; 40(5): 1063-71. PubMed

Kreuter A, Akgül B, Hufbauer M, Silling S, Oellig F, Wieland U. Two-factor Oncogenesis in a Human Papillomavirus 68-associated Penile Carcinoma. Acta Derm Venereol 2021; 101(2): adv00385. PubMed

Rokohl AC, Grajewski RS, Wawer Matos PA, Koch HL, Dewald F, Klein F, Fätkenheuer G, Lehmann C, Cursiefen C, Heindl LM. No secret hiding place? Absence of SARS-CoV-2 on the ocular surface of 1145 hospitalized patients in a pandemic area. Graefes Arch Clin Exp Ophthalmol 2021; 259(6): 1605-8. PubMed

Braun SA, Silling S, Schloer SM, Hofmann SC, Fritzen B, Oellig F, Lehmann P, Homey B, Assaf C, Emmert S, Fölster-Holst R, Tigges C, Wieland U, Kreuter A. Human Papillomavirus-type distribution in anogenital lesions of prepubertal children. J Eur Acad Dermatol Venereol 2021; 35(5): 1219-25. PubMed

Horn C, Augustin M, Ercanoglu MS, Heger E, Knops E, Bondet V, Duffy D, Chon SH, Nierhoff D, Oette M, Schäfer H, Vivaldi C, Held K, Anderson J, Geldmacher C, Suárez I, Rybniker J, Klein F, Fätkenheuer G, Müller-Trutwin M, Lehmann C. HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART. HIV Med 2021; 22(5): 397-408. PubMed

Krähling V, Halwe S, Rohde C, Becker D, Berghöfer S, Dahlke C, Eickmann M, Ercanoglu MS, Gieselmann L, Herwig A, Kupke A, Müller H, Neubauer-Rädel P, Klein F, Keller C, Becker S. Development and characterization of an indirect ELISA to detect SARS-CoV-2 spike protein-specific antibodies. J Immunol Methods 2021; 490: 112958. PubMed

Wieland U, Kreuter A. [Prevention of HPV-induced diseases by prophylactic vaccination]. Hautarzt 2021; 72(2): 106-13. PubMed

Bankwitz D, Bahai A, Labuhn M, Doepke M, Ginkel C, Khera T, Todt D, Ströh LJ, Dold L, Klein F, Klawonn F, Krey T, Behrendt P, Cornberg M, McHardy AC, Pietschmann T. Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies. Gut 2021; 70(9): 1734-45. PubMed

Meyer M, Rübsteck E, Lehmann C, Klein F, Gruell H, Hünseler C, Weber LT. [Prevalence of SARS-CoV-2 in children from a cohort of 2192 patients]. Monatsschr Kinderheilkd 2021; 169(1): 46-51. PubMed

Gambichler T, Dreißigacker M, Kasakovski D, Skrygan M, Wieland U, Silling S, Gravemeyer J, Melior A, Cherouny A, Stücker M, Stockfleth E, Sand M, Becker JC. Patched 1 expression in Merkel cell carcinoma. J Dermatol 2021; 48(1): 64-74. PubMed

Kreuter A, Oellig F, Kuntz T, Paschos A, Silling S, Akgül B, Wieland U. Acquired lymphangioma circumscriptum in high-grade penile intraepithelial neoplasia. Int J STD AIDS 2021; 32(1): 86-8. PubMed

Borghetti A, Ciccullo A, Lombardi F, Baldin G, Belmonti S, Prosperi M, Incardona F, Heger E, Borghi V, Sönnerborg A, Zazzi M, De Luca A, Di Giambenedetto S. Transmitted drug resistance to NRTIs and risk of virological failure in naïve patients treated with integrase inhibitors. HIV Med 2021; 22(1): 22-7. PubMed

Di Cristanziano V, Meyer-Schwickerath C, Eberhardt KA, Rybniker J, Heger E, Knops E, Hallek M, Klein F, Holtick U, Jung N. Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia. Bone Marrow Transplant 2021; 56(3): 716-9. PubMed

Grajewski RS, Rokohl AC, Becker M, Dewald F, Lehmann C, Fätkenheuer G, Cursiefen C, Klein F, Heindl LM. A missing link between SARS-CoV-2 and the eye?: ACE2 expression on the ocular surface. J Med Virol 2021; 93(1): 78-9. PubMed

Berzow D, Descamps D, Obermeier M, Charpentier C, Kaiser R, Guertler L, Eberle J, Wensing A, Sierra S, Ruelle J, Gomes P, Mansinho K, Taylor N, Jensen B, Döring M, Stürmer M, Rockstroh J, Camacho R. Human Immunodeficiency Virus-2 (HIV-2): A Summary of the Present Standard of Care and Treatment Options for Individuals Living with HIV-2 in Western Europe. Clin Infect Dis 2021; 72(3): 503-9. PubMed

2020

Imhof T, Rosenblatt K, Pryymachuk G, Weiland D, Noetzel N, Deschner J, Baris OR, Kimoloi S, Koch M, Wiesner RJ, Korkmaz Y. Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor. Sci Rep 2020; 10(1): 22037. PubMed

Waterboer T, Brenner N, Klussmann JP, Brennan P, Wieland U, Robbins HA. Study results and related evidence do not support use of HPV16 L1 DRH1 antibodies as a cancer screening test. EBioMedicine 2020; 62: 103143. PubMed

Kirschberg M, Heuser S, Marcuzzi GP, Hufbauer M, Seeger JM, Đukić A, Tomaić V, Majewski S, Wagner S, Wittekindt C, Würdemann N, Klussmann JP, Quaas A, Kashkar H, Akgül B. ATP synthase modulation leads to an increase of spare respiratory capacity in HPV associated cancers. Sci Rep 2020; 10(1): 17339. PubMed

Lentzsch AM, Dooling V, Wegner I, Di Cristanziano V, Sadda SR, Freund KB, Liakopoulos S. Acute Exudative Polymorphous Vitelliform Maculopathy Associated with Primary Epstein-Barr Virus Infection. Retin Cases Brief Rep 2020. PubMed

Stecher M, Chaillon A, Stephan C, Knops E, Kohmer N, Lehmann C, Eberle J, Bogner J, Spinner CD, Eis-Hübinger AM, Wasmuth JC, Schäfer G, Behrens G, Mehta SR, Vehreschild JJ, Hoenigl M. Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-2018(1). Emerg Infect Dis 2020; 26(10): 2439-43. PubMed

Koushk-Jalali B, Schürrle S, Kuntz T, Mitrakos G, Tigges C, Oellig F, Hammacher A, Silling S, Wieland U, Kreuter A. [Squamous cell carcinoma arising in oral lichen planus : Report of two cases]. Hautarzt 2020; 71(12): 1000-6. PubMed

Kuntz T, Koushk-Jalali B, Tigges C, Silling S, Oellig F, Has C, Hampl M, Wieland U, Kreuter A. Human Papillomavirus-induced Cutaneous and Mucosal Lesions in a Patient with Rothmund-Thomson Syndrome. Acta Derm Venereol 2020; 100(15): adv00252. PubMed

Theobald SJ, Kreer C, Khailaie S, Bonifacius A, Eiz-Vesper B, Figueiredo C, Mach M, Backovic M, Ballmaier M, Koenig J, Olbrich H, Schneider A, Volk V, Danisch S, Gieselmann L, Ercanoglu MS, Messerle M, Kaisenberg CV, Witte T, Klawonn F, Meyer-Hermann M, Klein F, Stripecke R. Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. PLoS Pathog 2020; 16(7): e1008560. PubMed

Koushk-Jalali B, Kuntz T, Tigges C, Gharevi NT, Wieland U, Kreuter A. Cervical trophic syndrome - a rare clinical variant of neural trophic syndrome. J Dtsch Dermatol Ges 2020; 18(12): 1486-7. PubMed

Goereci Y, Schweitzer F, Wellstein A, Silling S, Borchmann S, von Tresckow B, Adams O, Martin R, Schlamann M, Schroeter M, Fink GR, Wattjes MP, Warnke C. Clearance of JC polyomavirus from cerebrospinal fluid following treatment with interleukin-2 and pembrolizumab in an individual with progressive multifocal leukoencephalopathy and no underlying immune deficiency syndrome. Eur J Neurol 2020; 27(11): 2375-7. PubMed

Heinen S, Schulze N, Franke B, Klein F, Lehmann C, Vehreschild M, Gloistein C, Stecher M, Vehreschild JJ. HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies. BMC Bioinformatics 2020; 21(1): 290. PubMed

Wilden JJ, van Krüchten A, Gieselmann L, Hrincius ER, Deinhardt-Emmer S, Haupt KF, Preugschas HF, Niemann S, Ludwig S, Ehrhardt C. The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections. PLoS One 2020; 15(5): e0233052. PubMed

Ganzenmueller T, Kaiser R, Baier C, Wehrhane M, Hilfrich B, Witthuhn J, Flucht S, Heim A. Comparison of the performance of the Panther Fusion respiratory virus panel to R-Gene and laboratory developed tests for diagnostic and hygiene screening specimens from the upper and lower respiratory tract. J Med Microbiol 2020; 69(3): 427-35. PubMed

Di Cristanziano V, Weimer K, Böttcher S, Sarfo FS, Dompreh A, Cesar LG, Knops E, Heger E, Wirtz M, Kaiser R, Norman B, Phillips RO, Feldt T, Eberhardt KA. Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana. Viruses 2020; 12(2). PubMed

Bertling F, Kuntz T, Koushk-Jalali B, Oellig F, Wieland U, Kreuter A. [Persistent livid-erythematous flat node in the groin]. Hautarzt 2020; 71(5): 399-402. PubMed

Wieland U, Oellig F, Kreuter A. [Anal dysplasia and anal cancer]. Hautarzt 2020; 71(4): 284-92. PubMed

Kalusche S, Vanshylla K, Kleipass F, Gruell H, Müller B, Zeng Z, Koch K, Stein S, Marcotte H, Klein F, Dietrich U. Lactobacilli Expresing Broadly Neutralizing Nanobodies against HIV-1 as Potential Vectors fpr HIV-1 Prohylaxis? Vaccines 2020. Pubmed

Kaw S, Ananth S, Tsopoulidis N, Morath K, Coban BM, Hohenberger R, Bulut OC, Klein F, Stolp B, Fachler OT. Expression of HIV-1 pathogenesis factor NEF in CD4 T cells impairs antigen-specific B-cell function. EMBO J 2020. Pubmed

Schermer B, Fabretti F, Damagenz M, Di Cristanziano V, Heger E, Arjune S, Tanner NA, Imhof T, Koch M, Ladha A, Joung J, Gootenberg JS, Abudayyeh OO, Burst V, Zhang F, Klein F, Benzing T, Müller RU. Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay. PLoS One 2020. Pubmed

Eberhardt KA, Meyer-Schwickerath C, Heger E, Knops E, Lehmann C, Rybniker J, Schommers P, Eichenauer DA, Kurth F, Ramharter M, Kaiser R, Holtick U, Klein F, Jung N, Di Cristanziano V. RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients. Viruses 2020. Pubmed

Ramani A, Müller L, Ostermann PN*, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J. SARS-CoV-2 targets neurons of 3D human brain organoids. EMBO J 2020. Pubmed

Rokohl AC, Loreck N, Wawer Matos PA, Zwingelberg S, Augustin M, Dewald F, Grajewski RS, Klein F, Lehmann C, Heindl LM. More than loss of taste and smell: burning watering eyes in coronavirus disease 2019. Clin Microbiol Infect 2020. Pubmed

Kreer C, Zehner M, Weber T, Ercanoglu MS, Gieselmann L, Rohde C, Halwe S, Korenkov M, Schommers P, Vanshylla K, Di Cristanziano V, Janicki H, Brinker R, Ashurov A, Krähling V, Kupke A, Cohen-Dvashi H, Koch M, Eckert JM, Lederer S, Pfeifer S, Wolf T, Vehreschild MJGT, Wendtner C, Diskin R, Gruell H, Becker S, Klein F. Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients. Cell 2020. Pubmed

Stripecke R, Münz C, Schuringa JJ, Bissig KD, Soper B, Meeham T, Yao LC, Di Santo JP, Brehm M, Rodriguez E, Wege AK, Bonnet D, Guionaud S, Howard KE, Kitchen S, Klein F, Saeb-Parsy K, Sam J, Sharma AD, Trumpp A, Trusolino L, Bult C, Shultz L. Innovations, challenges, and minimal information for standardization of humanized mice. EMBO Mol Med 2020. Pubmed

Langerbeins P, Furstenau M, Gruell H, Klein F, Persigehl T, Rybniker J, Seeger-Nukpezah T, Kochanek M, Hallek M, Eichhorst B, Koehler P, Boll B. COVID-19 complicated by parainfluenza co-infection in a patient with chronic lymphocytic leukemia. Eur J Haematol 2020. PubMed

Augustin M, Schommers P, Suarez I, Koehler P, Gruell H, Klein F, Maurer C, Langerbeins P, Priesner V, Schmidt-Hellerau K, Malin JJ, Stecher M, Jung N, Wiesmuller G, Meissner A, Zweigner J, Langebartels G, Kolibay F, Suarez V, Burst V, Valentin P, Schedler D, Cornely OA, Hallek M, Fatkenheuer G, Rybniker J, Lehmann C. Rapid response infrastructure for pandemic preparedness in a tertiary care hospital: lessons learned from the COVID-19 outbreak in Cologne, Germany, February to March 2020. Euro Surveill 2020; 25(21). PubMed

Luers JC, Rokohl AC, Loreck N, Wawer Matos PA, Augustin M, Dewald F, Klein F, Lehmann C, Heindl LM. Reply to Gourtsoyannis. Clin Infect Dis 2020. PubMed

Heidepriem J, Krähling V, Dahlke C, Wolf T, Klein F, Addo MM, Becker S, Loeffler FF. Epitopes of Naturally Acquired and Vaccine-Induced Anti-Ebola Virus Glycoprotein Antibodies in Single Amino Acid Resolution. Biotechnol J 2020. PubMed

Luers JC, Rokohl AC, Loreck N, Wawer Matos PA, Augustin M, Dewald F, Klein F, Lehmann C, Heindl LM. Olfactory and Gustatory Dysfunction in Coronavirus Disease 19 (COVID-19). Clin Infect Dis 2020. Pubmed

Koehler P, Cornely OA, Böttiger BW, Dusse F, Eichenauer DA, Fuchs F, Hallek M, Jung N, Klein F, Persigehl T, Rybniker J, Kochanek M, Böll B, Shimabukuro-Vornhagen A. COVID-19 associated pulmonary aspergillosis. Mycoses 2020. Pubmed

Zehner M and Klein F. Antibody Teamwork against Ebola Virus Disease. Immunity 2020. Pubmed

Cohen-Dvashi H, Zehner M, Ehrhardt S, Katz M, Elad N, Klein F, Diskin R. Structural Basis for a Convergent Immune Response against Ebola Virus. Cell Host Microbe 2020. Pubmed

Niessl J, Baxter AE, Mendoza P, Jankovic M, Cohen YZ, Butler AL, Lu CL, Dubé M, Shimeliovich I, Gruell H, Klein F, Caskey M, Nussenzweig MC, Kaufmann DE. Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity. Nat Med 2020. Pubmed

Schommers P, Gruell H, Abernathy ME, Tran M-K, Dingens AS, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MV, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fätkenheuer G, Seaman MS, Bloom JD, Bjorkman J, Klein F. Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell 2020. Pubmed

Kreer C, Döring M, Lehnen N, Ercanoglu MS, Gieselmann L, Luca D, Jain K, Schommers P, Pfeifer N, Klein F. OpenPrimeR for multiplex amplification of highly diverse templates. J Immunol Methods 2020. Pubmed

Kreer C, Gruell H, Mora T, Walczak A.M. and Klein F. Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies. Vaccines 2020. Pubmed

Stanicek L, Lozano-Vidal N, Bink DI, Hooglugt A, Yao W, Wittig I, van Rijssel J, van Buul JD, van Bergen A, Klems A, Ramms AS, Le Noble F, Hofmann P, Szulcek R, Wang S, Offermanns S, Ercanoglu MS, Kwon HB, Stainier D, Huveneers S, Kurian L, Dimmeler S, Boon RA. Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function. Commun Biol 2020; 3(1): 265. PubMed

Neuhann F, de Forest A, Heger E, Nhlema A, Scheller C, Kaiser R, Steffen HM, Tweya H, Fatkenheuer G, Phiri S. Pretreatment resistance mutations and treatment outcomes in adults living with HIV-1: a cohort study in urban Malawi. AIDS Res Ther 2020; 17(1): 22. PubMed

Bastys T, Gapsys V, Walter H, Heger E, Doncheva NT, Kaiser R, de Groot BL, Kalinina OV. Non-active site mutants of HIV-1 protease influence resistance and sensitisation towards protease inhibitors. Retrovirology 2020; 17(1): 13. PubMed

Eberhard JM, Angin M, Passaes C, Salgado M, Monceaux V, Knops E, Kobbe G, Jensen B, Christopeit M, Kroger N, Vandekerckhove L, Badiola J, Bandera A, Raj K, van Lunzen J, Hutter G, Kuball JHE, Martinez-Laperche C, Balsalobre P, Kwon M, Diez-Martin JL, Nijhuis M, Wensing A, Martinez-Picado J, Schulze Zur Wiesch J, Saez-Cirion A. Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1. Sci Transl Med 2020; 12(542). PubMed

Schlösser M, Kartashev VV, Mikkola VH, Shemshura A, Saukhat S, Kolpakov D, Suladze A, Tverdokhlebova T, Hutt K, Heger E, Knops E, Bohm M, Di Cristanziano V, Kaiser R, Sonnerborg A, Zazzi M, Bobkova M, Sierra S. HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia. Viruses 2020; 12(4). PubMed

Wieland U, Oellig F, Kreuter A. Anal dysplasia and anal cancer. English version. Hautarzt 2020. PubMed

Köksal MO, Beka H, Evlice O, Ciftci S, Keskin F, Basaran S, Akgül B, Eraksoy H, Agacfidan A. Syphilis seroprevalence among HIV-infected males in Istanbul, Turkey. Rev Argent Microbiol 2020. PubMed

Suarez I, Gruell H, Heyckendorf J, Funger S, Lichtenstein T, Jung N, Lehmann C, Unnewehr M, Fatkenheuer G, Lange C, Rybniker J. Intensified adjunctive corticosteroid therapy for CNS tuberculomas. Infection 2020; 48(2): 289-93. PubMed

Stecher M, Classen A, Klein F, Lehmann C, Gruell H, Platten M, Wyen C, Behrens G, Fatkenheuer G, Vehreschild JJ. Systematic Review and Meta-analysis of Treatment Interruptions in Human Immunodeficiency Virus (HIV) Type 1-infected Patients Receiving Antiretroviral Therapy: Implications for Future HIV Cure Trials. Clin Infect Dis 2020; 70(7): 1406-17. PubMed

2019

De Luca A, Pezzotti P, Boucher C, Doring M, Incardona F, Kaiser R, Lengauer T, Pfeifer N, Schülter E, Vandamme AM, Zazzi M, Geretti AM, Euco HIVSG. Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey. PLoS One 2019; 14(11): e0225381. PubMed

Kuntz T, Viazis A, Koushk-Jalali B, Oellig F, Wieland U, Kreuter A. [Fast growing, bleeding nodule on the heel]. Hautarzt 2019; 70(11): 914-6. PubMed

Di Cristanziano V, D'Alfonso R, Berrilli F, Sarfo FS, Santoro M, Fabeni L, Knops E, Heger E, Kaiser R, Dompreh A, Phillips RO, Norman B, Feldt T, Eberhardt KA. Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana. PLoS One 2019; 14(9): e0221968. PubMed

Silling S, Soylemez U, Mauch C, Zigrino P, Kreuter A, Wieland U, Akgül B. Human papillomavirus type 197 is not associated with skin tumors. Int J Cancer 2019; 145(11): 3179-80. PubMed

Doring M, Kreer C, Lehnen N, Klein F, Pfeifer N. Modeling the Amplification of Immunoglobulins through Machine Learning on Sequence-Specific Features. Sci Rep 2019; 9(1): 10748. PubMed

Schleimann MH, Kobbero ML, Vibholm LK, Kjaer K, Giron LB, Busman-Sahay K, Chan CN, Nekorchuk M, Schmidt M, Wittig B, Damsgaard TE, Ahlburg P, Hellfritzsch MB, Zuwala K, Rothemejer FH, Olesen R, Schommers P, Klein F, Dweep H, Kossenkov A, Nyengaard JR, Estes JD, Abdel-Mohsen M, Ostergaard L, Tolstrup M, Sogaard OS, Denton PW. TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes. EBioMedicine 2019; 45: 328-40. PubMed

Vinken L, Fransen K, Cuypers L, Alexiev I, Balotta C, Debaisieux L, Seguin-Devaux C, Garcia Ribas S, Gomes P, Incardona F, Kaiser R, Ruelle J, Sayan M, Paraschiv S, Paredes R, Peeters M, Sonnerborg A, Vancutsem E, Vandamme AM, Van den Wijngaert S, Van Ranst M, Verhofstede C, Stadler T, Lemey P, Van Laethem K. Earlier Initiation of Antiretroviral Treatment Coincides With an Initial Control of the HIV-1 Sub-Subtype F1 Outbreak Among Men-Having-Sex-With-Men in Flanders, Belgium. Front Microbiol 2019; 10: 613. PubMed

Walker A, Ennker KS, Kaiser R, Lübke N, Timm J. A pan-genotypic Hepatitis C Virus NS5A amplification method for reliable genotyping and resistance testing. J Clin Virol 2019; 113: 8-13. PubMed

Stecher M, Schommers P, Schmidt D, Kollan C, Gunsenheimer-Bartmeyer B, Lehmann C, Platten M, Fatkenheuer G, Vehreschild JJ, ClinSurv Study G. Antiretroviral treatment indications and adherence to the German-Austrian treatment initiation guidelines in the German ClinSurv HIV Cohort between 1999 and 2016. Infection 2019; 47(2): 247-55. PubMed

Stecher M, Chaillon A, Eis-Hubinger AM, Lehmann C, Fatkenheuer G, Wasmuth JC, Knops E, Vehreschild JJ, Mehta S, Hoenigl M. Pretreatment human immunodeficiency virus type 1 (HIV-1) drug resistance in transmission clusters of the Cologne-Bonn region, Germany. Clin Microbiol Infect 2019; 25(2): 253 e1- e4. PubMed

Stecher M, Hoenigl M, Eis-Hubinger AM, Lehmann C, Fatkenheuer G, Wasmuth JC, Knops E, Vehreschild JJ, Mehta S, Chaillon A. Hotspots of Transmission Driving the Local Human Immunodeficiency Virus Epidemic in the Cologne-Bonn Region, Germany. Clin Infect Dis 2019; 68(9): 1539-46. PubMed

Verheyen J, Thielen A, Lübke N, Dirks M, Widera M, Dittmer U, Kordelas L, Daumer M, de Jong DCM, Wensing AMJ, Kaiser R, Nijhuis M, Esser S. Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Delta32 Homozygous Stem Cells. Clin Infect Dis 2019; 68(4): 684-7. PubMed

Popping S, Dalm V, Lübke N, Cristanziano VD, Kaiser R, Boucher CAB, Van Kampen JJA. Emergence and Persistence of Letermovir-Resistant Cytomegalovirus in a Patient With Primary Immunodeficiency. Open Forum Infect Dis 2019; 6(9): ofz375. PubMed

Ehrhardt SA, Zehner M, Krahling V, Cohen-Dvashi H, Kreer C, Elad N, Gruell H, Ercanoglu MS, Schommers P, Gieselmann L, Eggeling R, Dahlke C, Wolf T, Pfeifer N, Addo MM, Diskin R, Becker S, Klein F. Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV. Nat Med 2019. PubMed

Lübke N, Jensen B, Hüttig F, Feldt T, Walker A, Thielen A, Däumer M, Obermeier M, Kaiser R, Knops E, Heger E, Sierra S, Oette M, Lengauer T, Timm J, Häussinger D. Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R. N Engl J Med 2019; 381(9): 887-9. PubMed

Caskey M, Klein F, Nussenzweig MC. Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic. Nat Med 2019; 25(4): 547-53. PubMed

Kuntz T, Koushk-Jalali B, Tigges C, Silling S, di Cristanziano V, Wieland U, Oellig F, Kreuter A. [Atypical variant of hand-foot-mouth disease]. Hautarzt 2019. PubMed

Wieland U, Silling S, Hufbauer M, Mauch C, Zigrino P, Oellig F, Kreuter A, Akgül B. No Evidence for Role of Cutavirus in Malignant Melanoma. Emerg Infect Dis 2019; 25(8): 1600-16002. PubMed

Kirschberg M, Heuser S, Syed AS, Steger G, Majewski S, Hufbauer M, Akgül B. HPV8 activates cellular gene expression mainly through Sp1/3 binding sites. Virology 2019; 535: 136-43. PubMed

Oswald E, Kirschberg M, Aubin F, Alonso A, Hufbauer M, Akgül B, Auvinen E. BetaHPV E6 and E7 colocalize with NuMa in dividing keratinocytes. Virus Genes 2019. PubMed

Kreuter A, Mitrakos G, Koushk-Jalali B, Kuntz T, Oellig F, Tigges C, Silling S, Wieland U. Human Papillomavirus Type 16 Induced Squamous Cell Carcinoma (in situ) of the Toes. Acta Derm Venereol 2019. PubMed

Wieland U, Kreuter A. Anal cancer risk: HPV-based cervical screening programmes. Lancet Infect Dis 2019; 19(8): 799-800. PubMed

Koushk-Jalali B, Oellig F, Wieland U, Kreuter A. Herpes simplex vegetans in a patient with primary myelofibrosis. Infection 2019. PubMed

Schoofs T, Barnes CO, Suh-Toma N, Golijanin J, Schommers P, Gruell H, West AP, Jr., Bach F, Lee YE, Nogueira L, Georgiev IS, Bailer RT, Czartoski J, Mascola JR, Seaman MS, McElrath MJ, Doria-Rose NA, Klein F, Nussenzweig MC, Bjorkman PJ. Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity 2019; 50(6): 1513-29 e9. PubMed

Stecher M, Classen A, Klein F, Lehmann C, Gruell H, Platten M, Wyen C, Behrens G, Fatkenheuer G, Vehreschild JJ. Systematic Review And Meta-Analysis of Treatment Interruptions in HIV-1 Infected Patients Receiving Antiretroviral Therapy: Implications for Future HIV Cure Trials. Clin Infect Dis 2019. PubMed

Kreuter A, Oellig F, Silling S, Wieland U. [69-year-old male with white, non-wipeable plaques on the penis : Preparation for the medical specialist examination: Part 27]. Hautarzt 2019; 70(Suppl 1): 2-6. PubMed

Caskey M, Klein F, Nussenzweig MC. Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic. Nat Med 2019; 25(4): 547-53. PubMed

Taute S, Böhnke P, Sprissler J, Buchholz S, Hufbauer M, Akgül B, Steger G. The Protein Tyrosine Phosphatase H1 PTPH1 Supports Proliferation of Keratinocytes and is a Target of the Human Papillomavirus Type 8 E6 Oncogene. Cells 2019; 8(3). PubMed

Akgül B, Kirschberg M, Storey A, Hufbauer M. Human papillomavirus type 8 oncoproteins E6 and E7 cooperate in downregulation of the cellular checkpoint kinase-1. Int J Cancer 2019; 145(3): 797-806. PubMed

von der Grün J, Winkelmann R, Meissner M, Wieland U, Silling S, Martin D, Fokas E, Rödel C, Rödel F, Balermpas P. Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma. Front Oncol 2019; 9: 20. PubMed

Robinson DJ, Patel A, Purdie KJ, Wang J, Rizvi H, Hufbauer M, Ostano P, Akgül B, Chiorino G, Harwood CA, Bergamaschi D. Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma. J Invest Dermatol 2019; 139(8): 1658-71 e8. PubMed

Drössler L, Lehmann C, Topelt K, Nierhoff D, Vehreschild JJ, Rybniker J, Hallek M, Fischer J, Stormberg V, Fatkenheuer G, Wieland U, Jung N. HBsAg-negative/anti-HBc-positive patients treated with rituximab: prophylaxis or monitoring to prevent hepatitis B reactivation? Infection 2019; 47(2): 293-300. PubMed

Rödel F, Martin D, Balermpas P, Wieland U, Winkelmann R, Riekmann T, Falk S, Rödel C, Fokas E. Modulation of radiation sensitivity and antitumor immunity by viral pathogenic factors: Implications for radio-immunotherapy. Biochim Biophys Acta Rev Cancer 2019; 1871(1): 126-37. PubMed

Hanner S, Wieland U, Hartschuh W, Enk A, Toberer F. Merkel cell polyomavirus integration-PCR in bilateral metachronous Merkel cell carcinoma on the nose. J Eur Acad Dermatol Venereol 2019; 33(1): e16-e8. PubMed

2018

Marx B, Hufbauer M, Zigrino P, Majewski S, Markiefka B, Sachsenheimer T, Brügger B, Akgül B. Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis. Oncotarget 2018; 9(75): 34142-58. PubMed

Kreuter A, Koushk Jalali B, Tigges C, Silling S, Lehmann P, Wieland U. Juvenile Spring Eruption Associated With Parvovirus B19 Infection. JAMA Dermatol 2018; 154(11):1356-1357. PubMed

Bar-On Y, Gruell H, Schoofs T, Pai JA, Nogueira L, Butler AL, Millard K, Lehmann C, Suarez I, Oliveira TY, Karagounis T, Cohen YZ, Wyen C, Scholten S, Handl L, Belblidia S, Dizon JP, Vehreschild JJ, Witmer-Pack M, Shimeliovich I, Jain K, Fiddike K, Seaton KE, Yates NL, Horowitz J, Gulick RM, Pfeifer N, Tomaras GD, Seaman MS, Fatkenheuer G, Caskey M, Klein F, Nussenzweig MC. Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals. Nat Med 2018; 24(11):1701-1707. PubMed

Mendoza P, Gruell H, Nogueira L, Pai JA, Butler AL, Millard K, Lehmann C, Suarez I, Oliveira TY, Lorenzi JCC, Cohen YZ, Wyen C, Kümmerle T, Karagounis T, Lu CL, Handl L, Unson-O'Brien C, Patel R, Ruping C, Schlotz M, Witmer-Pack M, Shimeliovich I, Kremer G, Thomas E, Seaton KE, Horowitz J, West AP, Jr., Bjorkman PJ, Tomaras GD, Gulick RM, Pfeifer N, Fätkenheuer G, Seaman MS, Klein F, Caskey M, Nussenzweig MC. Combination therapy with anti-HIV-1 antibodies maintains viral suppression. Nature 2018; 561(7724): 479-84. PubMed

Kochanek M, Boll B, Shimabukuro-Vornhagen A, Welte T, Wieland U, Pletz M, Hallek M, Fätkenheuer G, Salzberger B. [The 2017/2018 influenza season-business as usual? : A statement of medical societies]. Internist 2018; 59(10):1122-1124. PubMed

Herrmann A, Sandmann L, Adams O, Herrmann D, Dirks M, Widera M, Westhaus S, Kaiser R, di Cristanziano V, Manns MP, Korth J, Richter N, Anastasiou O, Timm J, von Hahn T, Ciesek S. Role of BK polyomavirus (BKV) and Torque teno virus (TTV) in liver transplant recipients with renal impairment. J Med Microbiol 2018; 67(10): 1496-508. PubMed

Knops E, Sierra S, Kalaghatgi P, Heger E, Kaiser R, Kalinina OV. Epistatic Interactions in NS5A of Hepatitis C Virus Suggest Drug Resistance Mechanisms. Genes 2018; 9(7). PubMed

Kreuter A, Nasserani N, Tigges C, Oellig F, Silling S, Akgül B, Wieland U. Cutavirus Infection in Primary Cutaneous B- and T-Cell Lymphoma. JAMA Dermatol 2018; 154(8): 965-7. PubMed

Döring M, Buch J, Friedrich G, Pironti A, Kalaghatgi P, Knops E, Heger E, Obermeier M, Däumer M, Thielen A, Kaiser R, Lengauer T, Pfeifer N. geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data. Nucleic Acids Res 2018; 46(W1): W271-W7. PubMed

Matsuda M, Louvel S, Sugiura W, Haas A, Pfeifer N, Yokomaku Y, Iwatani Y, Kaiser R, Klimkait T. Performance Evaluation of a Genotypic Tropism Test Using HIV-1 CRF01_AE Isolates in Japan. Jpn J Infect Dis 2018; 71(4): 264-6. PubMed

Hufbauer M, Maltseva M, Meinrath J, Lechner A, Beutner D, Huebbers CU, Akgül B. HPV16 increases the number of migratory cancer stem cells and modulates their miRNA expression profile in oropharyngeal cancer. Int J Cancer 2018; 143(6): 1426-39. PubMed

Koushk Jalali B, Tigges C, Wieland U, Kreuter A. [A 10-Year-Old Boy with a Skin Rash on the Face and on Both Forearms]. Dtsch Med Wochenschr 2018; 143(8): 549-50. PubMed

Boucher CA, Bobkova MR, Geretti AM, Hung CC, Kaiser R, Marcelin AG, Streinu-Cercel A, van Wyk J, Dorr P, Vandamme AM. State of the Art in HIV Drug Resistance: Science and Technology Knowledge Gap. AIDS Rev 2018; 20(1): 27-42. PubMed

Boucher CA, Bobkova MR, Hung CC, Kaiser R, Marcelin AG, Streinu-Cercel A, van Wyk J, Dorr P, Vandamme AM. State of the Art in HIV Drug Resistance: Surveillance and Regional Gaps. AIDS Rev 2018; 20(1): 43-57. PubMed

Kreuter A, Hufbauer M, Silling S, Oellig F, Akgü l B, Wieland U. Simultaneous Induction of Benign Condyloma and High-grade Anal Dysplasia Induced by Low-risk Human Papillomavirus Type 42. Acta Derm Venereol 2018; 98(6): 616-7. PubMed

Kreuter A, Pantelaki I, Michalowitz AL, Wieland U, Cerroni L, Oellig F, Tigges C. CD30-positive primary cutaneous anaplastic large cell lymphoma with coexistent pseudocarcinomatous hyperplasia. Clin Exp Dermatol 2018; 43(5): 585-8. PubMed

Whitmer SLM, Strecker T, Cadar D, Dienes HP, Faber K, Patel K, Brown SM, Davis WG, Klena JD, Rollin PE, Schmidt-Chanasit J, Fichet-Calvet E, Noack B, Emmerich P, Rieger T, Wolff S, Fehling SK, Eickmann M, Mengel JP, Schultze T, Hain T, Ampofo W, Bonney K, Aryeequaye JND, Ribner B, Varkey JB, Mehta AK, Lyon GM, 3rd, Kann G, De Leuw P, Schuettfort G, Stephan C, Wieland U, Fries JWU, Kochanek M, Kraft CS, Wolf T, Nichol ST, Becker S, Ströher U, Günther S. New Lineage of Lassa Virus, Togo, 2016. Emerg Infect Dis 2018; 24(3): 599-602. PubMed

Gross GE, Werner RN, Becker JC, Brockmeyer NH, Esser S, Hampl M, Hommel S, Jongen J, Mestel DS, Meyer T, Petry KU, Plettenberg A, Püschel K, Schneede P, Schöfer H, Sotlar K, Weyandt G, Wieland U, Wiese-Posselt M, Nast A. S2k guideline: HPV-associated lesions of the external genital region and the anus - anogenital warts and precancerous lesions of the vulva, the penis, and the peri- and intra-anal skin (short version). J Dtsch Dermatol Ges 2018; 16(2): 242-55. PubMed

Wieland U, Kreuter A. The importance of HPV16 in anal cancer prevention. Lancet Infect Dis 2018; 18(2): 131-2. PubMed

Rödel F, Steinhauser K, Kreis NN, Friemel A, Martin D, Wieland U, Rave-Frank M, Balermpas P, Fokas E, Louwen F, Rodel C, Yuan J. Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy. Radiother Oncol 2018; 126(2): 214-21. PubMed

Knops E, Heger E, Koenig C, Moebius U, Lübke N, Kaiser R, Di Cristanziano V, Hüsgen L, Kocyigit C, Rupp J, Sierra S. Accurate hepatitis C virus genotyping and selection of optimal therapy: lessons from a St Petersburg strain infection. Clin Microbiol Infect 2018; 24(4): 440-1. PubMed

Bouwes Bavinck JN, Feltkamp MCW, Green AC, Fiocco M, Euvrard S, Harwood CA, Nasir S, Thomson J, Proby CM, Naldi L, Diphoorn JCD, Venturuzzo A, Tessari G, Nindl I, Sampogna F, Abeni D, Neale RE, Goeman JJ, Quint KD, Halk AB, Sneek C, Genders RE, de Koning MNC, Quint WGV, Wieland U, Weissenborn S, Waterboer T, Pawlita M, Pfister H, group E-H-U-C. Human papillomavirus and posttransplantation cutaneous squamous cell carcinoma: A multicenter, prospective cohort study. Am J Transplant 2018; 18(5): 1220-30. PubMed

Pett SL, Amin J, Horban A, Andrade-Villanueva J, Losso M, Porteiro N, Madero JS, Belloso W, Tu E, Silk D, Kelleher A, Harrigan R, Clark A, Sugiura W, Wolff M, Gill J, Gatell J, Clarke A, Ruxrungtham K, Prazuck T, Kaiser R, Woolley I, Alberto Arnaiz J, Cooper D, Rockstroh JK, Mallon P, Emery S, group Ms. Week 96 results of the randomized, multicentre Maraviroc Switch (MARCH) study. HIV Med 2018; 19(1): 65-71. PubMed

2017

Hasche D, Stephan S, Braspenning-Wesch I, Mikulec J, Niebler M, Gröne HJ, Flechtenmacher C, Akgül B, Rösl F, Vinzon SE. The interplay of UV and cutaneous papillomavirus infection in skin cancer development. PLoS Pathog 2017; 13(11): e1006723. PubMed

Taute S, Pfister HJ, Steger G. Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis. Front Microbiol 2017; 8: 2197. PubMed

Bouwes Bavinck JN, Feltkamp MCW, Green AC, Fiocco M, Euvrard S, Harwood CA, Nasir S, Thomson J, Proby CM, Naldi L, Diphoorn JCD, Venturuzzo A, Tessari G, Nindl I, Sampogna F, Abeni D, Neale RE, Goeman JJ, Quint KD, Halk AB, Sneek C, Genders RE, de Koning MNC, Quint WGV, Wieland U, Weissenborn S, Waterboer T, Pawlita M, Pfister H, group E-H-U-C. Human papillomavirus and posttransplantation cutaneous squamous cell carcinoma: A multicenter, prospective cohort study. Am J Transplant 2017. PubMed

Zaki M, Thoenes M, Kawalia A, Nürnberg P, Kaiser R, Heller R, Bolz HJ. Recurrent and Prolonged Infections in a Child with a Homozygous IFIH1 Nonsense Mutation. Front Genet 2017; 8: 130. PubMed

Kreuter A, Silling S, Oellig F, Wieland U. Human Papillomavirus-Induced Atypical Pigmented High-grade Dysplasia of the Scrotum. JAMA Dermatol 2017; 153(12): 1332-4. PubMed

Marx B, Miller-Lazic D, Doorbar J, Majewski S, Hofmann K, Hufbauer M, Akgül B. HPV8-E6 Interferes with Syntenin-2 Expression through Deregulation of Differentiation, Methylation and Phosphatidylinositide-Kinase Dependent Mechanisms. Front Microbiol 2017; 8: 1724. PubMed

Yao X, Tan J, Lim KJ, Koh J, Ooi WF, Li Z, Huang D, Xing M, Chan YS, Qu JZ, Tay ST, Wijaya G, Lam YN, Hong JH, Lee-Lim AP, Guan P, Ng MSW, He CZ, Lin JS, Nandi T, Qamra A, Xu C, Myint SS, Davies JOJ, Goh JY, Loh G, Tan BC, Rozen SG, Yu Q, Tan IBH, Cheng CWS, Li S, Chang KTE, Tan PH, Silver DL, Lezhava A, Steger G, Hughes JR, Teh BT, Tan P. VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma. Cancer Discov 2017; 7(11): 1284-305. PubMed

D'Alfonso R, Santoro M, Essi D, Monsia A, Kabore Y, Gle C, Di Cave D, Sorge RP, Di Cristanziano V, Berrilli F. Blastocystis in Cote d'Ivoire: molecular identification and epidemiological data. Eur J Clin Microbiol Infect Dis 2017; 36(11): 2243-50. PubMed

Heger E, Kaiser R, Knops E, Neumann-Fraune M, Schuelter E, Pironti A, Lengauer T, Walter H, Sierra S. Results of the first international HIV-1 coreceptor proficiency panel test. J Clin Virol 2017; 93: 53-6. PubMed

Walker A, Filke S, Lübke N, Obermeier M, Kaiser R, Haussinger D, Timm J, Bock HH. Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure. Virol J 2017; 14(1): 106. PubMed

Gruell H, Hamacher L, Jennissen V, Tuchscherer A, Ostendorf N, Löffler T, Hallek M, Kochanek M, Tannich E, Boll B, Fätkenheuer G. On Taking a Different Route: An Unlikely Case of Malaria by Nosocomial Transmission. Clin Infect Dis 2017; 65(8): 1404-6. PubMed 

Hufbauer M, Akgül B. Molecular Mechanisms of Human Papillomavirus Induced Skin Carcinogenesis. Viruses 2017; 9(7). PubMed 

Gilles R, Herling M, Holtick U, Heger E, Awerkiew S, Fish I, Höller K, Sierra S, Knops E, Kaiser R, Scheid C, Di Cristanziano V. Dynamics of Torque Teno virus viremia could predict risk of complications after allogeneic hematopoietic stem cell transplantation. Med Microbiol Immunol 2017. PubMed

Kreuter A, Pantelaki I, Tigges C, Oellig F, Wieland U. A persistent puritic rash of the chest. Lancet Oncol 2017; 18(7): e424.  

Lanfredini S, Olivero C, Borgogna C, Calati F, Powell K, Davies KJ, De Andrea M, Harries S, Tang HKC, Pfister H, Gariglio M, Patel GK. HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion. J Invest Dermatol 2017. PubMed 

Pantelaki I, Tigges C, Nussbaum T, Oellig F, Wieland U, Kreuter A. Complete remission of primary cutaneous intravascular large B-cell lymphoma with R-CHOP followed by rituximab monotherapy. Dermatol Ther 2017. PubMed 

Wieland U, Kreuter A. Kondylome bei HIV-Infizierten [Genital warts in HIV-infected individuals]. Hautarzt 2017; 68(3): 192-8. PubMed

Walker A, Bergmann M, Camdereli J, Kaiser R, Lubke N, Timm J. A genotype independent, full-genome reverse-transcription protocol for HCV genotyping and resistance testing. J Clin Virol 2017; 91: 42-8. PubMed

Gruell H, Klein F. Progress in HIV-1 antibody research using humanized mice. Curr Opin HIV AIDS 2017; 12(3): 285-93. PubMed

Balermpas P, Martin D, Wieland U, Rave-Frank M, Strebhardt K, Rödel C, Fokas E, Rödel F. Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy. Oncoimmunology 2017; 6(3): e1288331. PubMed

Höller K, Fabeni L, Herling M, Holtick U, Scheid C, Knops E, Lübke N, Kaiser R, Pfister H, Di Cristanziano V. Dynamics of BKPyV reactivation and risk of hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Eur J Haematol 2017. PubMed

Pironti A, Pfeifer N, Walter H, Jensen BO, Zazzi M, Gomes P, Kaiser R, Lengauer T. Using drug exposure for predicting drug resistance - A data-driven genotypic interpretation tool. PLoS One 2017; 12(4): e0174992. PubMed

Ojeh N, Akgül B, Tomic-Canic M, Philpott M, Navsaria H. In vitro skin models to study epithelial regeneration from the hair follicle. PLoS One 2017; 12(3): e0174389. PubMed

Gültekin M, Akgül B. HPV screening in Islamic countries. Lancet Infect Dis 2017; 17(4): 368. PubMed

Schroeder L, Herwartz C, Jordanovski D, Steger G. ZNF395 Is an Activator of a Subset of IFN-Stimulated Genes. Mediators Inflamm 2017; 2017: 1248201. PubMed

Nishimura Y, Gautam R, Chun TW, Sadjadpour R, Foulds KE, Shingai M, Klein F, Gazumyan A, Golijanin J, Donaldson M, Donau OK, Plishka RJ, Buckler-White A, Seaman MS, Lifson JD, Koup RA, Fauci AS, Nussenzweig MC, Martin MA. Early antibody therapy can induce long-lasting immunity to SHIV. Nature 2017; 543(7646): 559-63. PubMed

Böttcher S, Obermeier PE, Diedrich S, Kabore Y, D'Alfonso R, Pfister H, Kaiser R, Di Cristanziano V. Genome Sequence of Novel Human Parechovirus Type 17. Genome Announc 2017; 5(8). PubMed

Caskey M, Schoofs T, Gruell H, Settler A, Karagounis T, Kreider EF, Murrell B, Pfeifer N, Nogueira L, Oliveira TY, Learn GH, Cohen YZ, Lehmann C, Gillor D, Shimeliovich I, Unson-O'Brien C, Weiland D, Robles A, Kümmerle T, Wyen C, Levin R, Witmer-Pack M, Eren K, Ignacio C, Kiss S, West AP, Jr., Mouquet H, Zingman BS, Gulick RM, Keler T, Bjorkman PJ, Seaman MS, Hahn BH, Fätkenheuer G, Schlesinger SJ, Nussenzweig MC, Klein F. Antibody 10-1074 suppresses viremia in HIV-1-infected individuals. Nat Med 2017; 23(2): 185-91. PubMed 

Gozlan Y, Ben-Ari Z, Moscona R, Shirazi R, Rakovsky A, Kabat A, Veizman E, Berdichevski T, Weiss P, Cohen-Ezra O, Lurie Y, Gafanovich I, Braun M, Cohen-Naftaly M, Shlomai A, Shibolet O, Zigmond E, Zuckerman E, Carmiel-Haggai M, Nimer A, Hazzan R, Maor Y, Kitay-Cohen Y, Shemer-Avni Y, Kra-Oz Z, Schreiber L, Peleg O, Sierra S, Harrigan PR, Mendelson E, Mor O. HCV genotype-1 subtypes and resistance-associated substitutions in drug-naive and in direct-acting antiviral treatment failure patients. Antivir Ther 2017. PubMed 

Herberhold S, Hellmich M, Panning M, Bartok E, Silling S, Akgül B, Wieland U. Human polyomavirus and human papillomavirus prevalence and viral load in non-malignant tonsillar tissue and tonsillar carcinoma. Med Microbiol Immunol 2017; 206(2): 93-103. PubMed 

Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll UM, Seegobin S, Dewor M, Hallek M, Marquardt Y, Fietkau K, Heise R, Huth S, Pfister H, Bernhagen J, Bucala R, Baron JM, Fingerle-Rowson G. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. Faseb j 2017; 31(2): 526-43. PubMed 

Oette M, Wieland U, Schunemann M, Haes J, Reuter S, Jensen BE, Sagir A, Pfister H, Haussinger D. Anal chromoendoscopy using gastroenterological video-endoscopes: A new method to perform high resolution anoscopy for diagnosing intraepithelial neoplasia and anal carcinoma in HIV-infected patients. Z Gastroenterol 2017; 55(1): 23-31. PubMed 

Pironti A, Walter H, Pfeifer N, Knops E, Lubke N, Buch J, Di Giambenedetto S, Kaiser R, Lengauer T. Determination of Phenotypic Resistance Cutoffs From Routine Clinical Data. J Acquir Immune Defic Syndr 2017; 74(5): e129-e37. PubMed 

Schwarze-Zander C, Draenert R, Lehmann C, Stecher M, Boesecke C, Sammet S, Wasmuth JC, Seybold U, Gillor D, Wieland U, Kummerle T, Strassburg CP, Mankertz A, Eis-Hubinger AM, Jager G, Fatkenheuer G, Bogner JR, Rockstroh JK, Vehreschild JJ. Measles, mumps, rubella and VZV: importance of serological testing of vaccine-preventable diseases in young adults living with HIV in Germany. Epidemiol Infect 2017; 145(2): 236-44. PubMed 

Gambichler T, Wieland U, Silling S, Dreissigacker M, Schaller J, Schulze HJ, Oellig F, Kreuter A, Stucker M, Bechara FG, Stockfleth E, Becker JC. Left-sided laterality of Merkel cell carcinoma in a German population: more than just sun exposure. J Cancer Res Clin Oncol 2017; 143(2): 347-50. PubMed 

Knops E, Schubel N, Heger E, Neumann-Fraune M, Kaiser R, Inden S, Kalaghatgi P, Sierra S. HCV Resistance Profile Evolution in a GT1b, DAA-Naive Patient Before, On, and After Failing Triple DAA Therapy. Clin Gastroenterol Hepatol 2017; 15(2): 307-9. PubMed 

Gambichler T, Mohtezebsade S, Wieland U, Silling S, Hoh AK, Dreissigacker M, Schaller J, Schulze HJ, Oellig F, Kreuter A, Stockfleth E, Stucker M, Bechara FG, Becker JC. Prognostic relevance of high atonal homolog-1 expression in Merkel cell carcinoma. J Cancer Res Clin Oncol 2017; 143(1): 43-9. PubMed

2016

Doring M, Borrego P, Buch J, Martins A, Friedrich G, Camacho RJ, Eberle J, Kaiser R, Lengauer T, Taveira N, Pfeifer N. A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support. Retrovirology 2016; 13(1): 85. PubMed 

Caskey M, Klein F, Nussenzweig MC. Broadly Neutralizing Antibodies for HIV-1 Prevention or Immunotherapy. N Engl J Med 2016; 375(21): 2019-21. PubMed 

Koksal MO, Beka H, Demirci M, Kadioglu A, Agacfidan A, Akgül B. Prevalence and genotyping of Chlamydia trachomatis in symptomatic male patients from Istanbul, Turkey. Springerplus 2016; 5(1): 1706. PubMed 

Demir M, Phiri S, Kaiser R, Chaweza T, Neuhann F, Tweya H, Fatkenheuer G, Steffen HM. HIV/Hepatitis C Virus Co-infection among Adults Beginning Antiretroviral Therapy, Malawi. Emerg Infect Dis 2016; 22(11): 2018-20. PubMed 

Heger E, Theis AA, Remmel K, Walter H, Pironti A, Knops E, Di Cristanziano V, Jensen B, Esser S, Kaiser R, Lubke N. Development of a phenotypic susceptibility assay for HIV-1 integrase inhibitors. J Virol Methods 2016; 238: 29-37. PubMed 

Iebba V, Santangelo F, Totino V, Pantanella F, Monsia A, Di Cristanziano V, Di Cave D, Schippa S, Berrilli F, D'Alfonso R. Gut microbiota related to Giardia duodenalis, Entamoeba spp. and Blastocystis hominis infections in humans from Cote d'Ivoire. J Infect Dev Ctries 2016; 10(9): 1035-41. PubMed 

Kreuter A, Wieland U. Condylomata acuminata of HIV-positive men may harbour focal areas of dysplasia: relevant implications for the management of human papillomavirus-induced disease in high-risk patients. Br J Dermatol 2016; 175(4): 672-3. PubMed 

Gristick HB, von Boehmer L, West AP, Jr., Schamber M, Gazumyan A, Golijanin J, Seaman MS, Fatkenheuer G, Klein F, Nussenzweig MC, Bjorkman PJ. Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat Struct Mol Biol 2016; 23(10): 906-15. PubMed 

Schulze MH, Volker FM, Lugert R, Cooper P, Hasenclever K, Gross U, Pfister H, Silling S. High prevalence of human papillomaviruses in Ghanaian pregnant women. Med Microbiol Immunol 2016; 205(6): 595-602. PubMed 

Deshmukh J, Pofahl R, Pfister H, Haase I. Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis. Oncotarget 2016; 7(36): 57841-50. PubMed 

Kreuter A, Siorokos C, Oellig F, Silling S, Pfister H, Wieland U. High-grade Dysplasia in Anogenital Warts of HIV-Positive Men. JAMA Dermatol 2016; 152(11): 1225-30. PubMed 

Rödel F, Martin D, Helmke C, Balermpas P, Fokas E, Wieland U, Rave-Frank M, Kitz J, Matthess Y, Raab M, Strebhardt K, Rödel C. Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy. Oncotarget 2016; 7(33): 53339-49. PubMed 

Kartashev V, Doring M, Nieto L, Coletta E, Kaiser R, Sierra S. New findings in HCV genotype distribution in selected West European, Russian and Israeli regions. J Clin Virol 2016; 81: 82-9. PubMed 

Scheid JF, Horwitz JA, Bar-On Y, Kreider EF, Lu CL, Lorenzi JC, Feldmann A, Braunschweig M, Nogueira L, Oliveira T, Shimeliovich I, Patel R, Burke L, Cohen YZ, Hadrigan S, Settler A, Witmer-Pack M, West AP, Jr., Juelg B, Keler T, Hawthorne T, Zingman B, Gulick RM, Pfeifer N, Learn GH, Seaman MS, Bjorkman PJ, Klein F, Schlesinger SJ, Walker BD, Hahn BH, Nussenzweig MC, Caskey M. HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption. Nature 2016; 535(7613): 556-60. PubMed 

Walch-Ruckheim B, Pahne-Zeppenfeld J, Fischbach J, Wickenhauser C, Horn LC, Tharun L, Buttner R, Mallmann P, Stern P, Kim YJ, Bohle RM, Rube C, Stroder R, Juhasz-Boss I, Solomayer EF, Smola S. STAT3/IRF1 Pathway Activation Sensitizes Cervical Cancer Cells to Chemotherapeutic Drugs. Cancer Res 2016; 76(13): 3872-83. PubMed 

Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, Oliveira T, Lorenzi JC, Parrish EH, Learn GH, West AP, Jr., Bjorkman PJ, Schlesinger SJ, Seaman MS, Czartoski J, McElrath MJ, Pfeifer N, Hahn BH, Caskey M, Nussenzweig MC. HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science 2016; 352(6288): 997-1001. PubMed 

Kalaghatgi P, Sikorski AM, Knops E, Rupp D, Sierra S, Heger E, Neumann-Fraune M, Beggel B, Walker A, Timm J, Walter H, Obermeier M, Kaiser R, Bartenschlager R, Lengauer T. Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents. PLoS One 2016; 11(5): e0155869. PubMed 

Kreuter A, Wieland U. Azithromycin versus Doxycycline for Chlamydia. N Engl J Med 2016; 374(18): 1786-7. PubMed 

Riemenschneider M, Cashin KY, Budeus B, Sierra S, Shirvani-Dastgerdi E, Bayanolhagh S, Kaiser R, Gorry PR, Heider D. Genotypic Prediction of Co-receptor Tropism of HIV-1 Subtypes A and C. Sci Rep 2016; 6: 24883. PubMed 

Gautam R, Nishimura Y, Pegu A, Nason MC, Klein F, Gazumyan A, Golijanin J, Buckler-White A, Sadjadpour R, Wang K, Mankoff Z, Schmidt SD, Lifson JD, Mascola JR, Nussenzweig MC, Martin MA. A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges. Nature 2016; 533(7601): 105-9. PubMed 

Pett SL, Amin J, Horban A, Andrade-Villanueva J, Losso M, Porteiro N, Sierra Madero J, Belloso W, Tu E, Silk D, Kelleher A, Harrigan R, Clark A, Sugiura W, Wolff M, Gill J, Gatell J, Fisher M, Clarke A, Ruxrungtham K, Prazuck T, Kaiser R, Woolley I, Arnaiz JA, Cooper D, Rockstroh JK, Mallon P, Emery S. Maraviroc, as a Switch Option, in HIV-1-infected Individuals With Stable, Well-controlled HIV Replication and R5-tropic Virus on Their First Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Plus Ritonavir-boosted Protease Inhibitor Regimen: Week 48 Results of the Randomized, Multicenter MARCH Study. Clin Infect Dis 2016; 63(1): 122-32. PubMed 

Fuchs W, Wieland U, Skaletz-Rorowski A, Brockmeyer NH, Swoboda J, Kreuter A, Michalik C, Potthoff A. The male ScreenING Study: prevalence of HPV-related genital and anal lesions in an urban cohort of HIV-positive men in Germany. J Eur Acad Dermatol Venereol 2016; 30(6): 995-1001. PubMed 

TenoRes_Study_Grp. Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study. Lancet Infect Dis 2016; 16(5): 565-75. PubMed 

De Luca A, Flandre P, Dunn D, Zazzi M, Wensing A, Santoro MM, Gunthard HF, Wittkop L, Kordossis T, Garcia F, Castagna A, Cozzi-Lepri A, Churchill D, De Wit S, Brockmeyer NH, Imaz A, Mussini C, Obel N, Perno CF, Roca B, Reiss P, Schülter E, Torti C, van Sighem A, Zangerle R, Descamps D. Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen. J Antimicrob Chemother 2016; 71(5): 1352-60. PubMed 

Heuser S, Hufbauer M, Steiger J, Marshall J, Sterner-Kock A, Mauch C, Zigrino P, Akgül B. The fibronectin/alpha3beta1 integrin axis serves as molecular basis for keratinocyte invasion induced by betaHPV. Oncogene 2016; 35(34): 4529-39. PubMed 

Kreuter A, Knispel S, Wieland U, Oellig F, Tigges C. Complete resolution of febrile ulceronecrotic Mucha-Habermann disease following infliximab therapy. J Dtsch Dermatol Ges 2016; 14(2): 184-6. PubMed 

Platten M, Jung N, Trapp S, Flossdorf P, Meyer-Olson D, Schulze Zur Wiesch J, Stephan C, Mauss S, Weiss V, von Bergwelt-Baildon M, Rockstroh J, Fatkenheuer G, Lehmann C. Cytokine and Chemokine Signature in Elite Versus Viremic Controllers Infected with HIV. AIDS Res Hum Retroviruses 2016; 32(6): 579-87. PubMed 

Nussbaum T, Tigges C, Kirschke J, Oellig F, v Verschuer U, Wieland U, Kreuter A. [Cutaneous involvement in chronic myelomonocytic leukemia--a possible indicator for transition into acute leucaemia]. Dtsch Med Wochenschr 2016; 141(1): 47-50. PubMed 

Herling M, Schroder L, Awerkiew S, Chakupurakal G, Holtick U, Kaiser R, Pfister H, Scheid C, Di Cristanziano V. Persistent CMV infection after allogeneic hematopoietic stem cell transplantation in a CMV-seronegative donor-to-positive recipient constellation: Development of multidrug resistance in the absence of anti-viral cellular immunity. J Clin Virol 2016; 74: 57-60. PubMed 

Akkina R, Allam A, Balazs AB, Blankson JN, Burnett JC, Casares S, Garcia JV, Hasenkrug KJ, Kashanchi F, Kitchen SG, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, Sanders-Beer BE, Shultz LD, Zack JA. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. AIDS Res Hum Retroviruses 2016; 32(2): 109-19. PubMed 

Heuser S, Hufbauer M, Marx B, Tok A, Majewski S, Pfister H, Akgül B. The levels of epithelial anchor proteins beta-catenin and zona occludens-1 are altered by E7 of human papillomaviruses 5 and 8. J Gen Virol 2016; 97(2): 463-72. PubMed 

Fuchs W, Kreuter A, Hellmich M, Potthoff A, Swoboda J, Brockmeyer NH, Wieland U. Asymptomatic anal sexually transmitted infections in HIV-positive men attending anal cancer screening. Br J Dermatol 2016; 174(4): 831-8. PubMed 

Neogi U, Haggblom A, Singh K, Rogers LC, Rao SD, Amogne W, Schülter E, Zazzi M, Arnold E, Sarafianos SG, Sonnerborg A. Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries. J Antimicrob Chemother 2016; 71(2): 367-71. PubMed 

Noguera-Julian M, Cozzi-Lepri A, Di Giallonardo F, Schuurman R, Däumer M, Aitken S, Ceccherini-Silberstein F, D'Arminio Monforte A, Geretti AM, Booth CL, Kaiser R, Michalik C, Jansen K, Masquelier B, Bellecave P, Kouyos RD, Castro E, Furrer H, Schultze A, Gunthard HF, Brun-Vezinet F, Metzner KJ, Paredes R. Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants. Clin Microbiol Infect 2016; 22(2): 191-200. PubMed 

Hermans LE, Svicher V, Pas SD, Salpini R, Alvarez M, Ben Ari Z, Boland G, Bruzzone B, Coppola N, Seguin-Devaux C, Dyda T, Garcia F, Kaiser R, Kose S, Krarup H, Lazarevic I, Lunar MM, Maylin S, Micheli V, Mor O, Paraschiv S, Paraskevis D, Poljak M, Puchhammer-Stockl E, Simon F, Stanojevic M, Stene-Johansen K, Tihic N, Trimoulet P, Verheyen J, Vince A, Weis N, Yalcinkaya T, Lepej SZ, Perno C, Boucher CA, Wensing AM. Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE). J Infect Dis 2016; 213(1): 39-48. PubMed 

Silling S, Wieland U, Fingerle V, Rasokat H, Fabri M. Painful blister-free HSV-type 1 reactivation on the site of acute Lyme borreliosis. J Eur Acad Dermatol Venereol 2016; 30(7): 1217-8. PubMed

2015

Di Cristanziano V, Bottcher S, Diedrich S, Timmen-Wego M, Knops E, Lubke N, Kaiser R, Pfister H, Kabore Y, D'Alfonso R. Erratum to "Detection and characterization of enteroviruses and parechoviruses in healthy people living in the South of Cote d'Ivoire" [J. Clin. Virol. 71 (2015) 40-43]. J Clin Virol 2015; 72: 153. PubMed 

Esser S, Kreuter A, Oette M, Gingelmaier A, Mosthaf F, Sautter-Bihl ML, Jongen J, Brockmeyer NH, Eldering G, Swoboda J, Postel N, Degen O, Schalk H, Jessen A, Knechten H, Thoden J, Stellbrink HJ, Schafberger A, Wieland U. German-Austrian guidelines on anal dysplasia and anal cancer in HIV-positive individuals: prevention, diagnosis, and treatment. J Dtsch Dermatol Ges 2015; 13(12): 1302-19. PubMed 

Kreuter A, Esser S, Wieland U. Prevention of Anal Carcinoma. Dtsch Arztebl Int 2015; 112(43): 739. PubMed 

Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A, Sanders RW, Moore JP, Bjorkman PJ, Seaman MS, Walker BD, Klein F, Nussenzweig MC. A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. PLoS Pathog 2015; 11(10): e1005238. PubMed 

Hufbauer M, Cooke J, van der Horst GT, Pfister H, Storey A, Akgül B. Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis. Mol Cancer 2015; 14: 183. PubMed 

Zolla-Pazner S, Cohen SS, Boyd D, Kong XP, Seaman M, Nussenzweig M, Klein F, Overbaugh J, Totrov M. Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity. J Virol 2015; 90(2): 636-49. PubMed 

Lee JH, Leaman DP, Kim AS, Torrents de la Pena A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, Klasse PJ, Sanders RW, Zwick MB, Wilson IA, Ward AB. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun 2015; 6: 8167. PubMed 

Cristanziano VD, Bottcher S, Diedrich S, Timmen-Wego M, Knops E, Lubke N, Kaiser R, Pfister H, Kabore Y, D'Alfonso R. Detection and characterization of enteroviruses and parechoviruses in healthy people living in the South of Cote d'Ivoire. J Clin Virol 2015; 71: 40-3. PubMed 

Di Cristanziano V, Timmen-Wego M, Lubke N, Kaiser R, Pfister H, Di Cave D, Berrilli F, Kabore Y, R DA. Application of Luminex Gastrointestinal Pathogen Panel to human stool samples from Cote d'Ivoire. J Infect Dev Ctries 2015; 9(8): 884-9. PubMed 

Wieland U, Hellmich M, Wetendorf J, Potthoff A, Hofler D, Swoboda J, Fuchs W, Brockmeyer N, Pfister H, Kreuter A. Smoking and anal high-risk human papillomavirus DNA loads in HIV-positive men who have sex with men. Int J Med Microbiol 2015; 305(7): 689-96. PubMed 

Doyle T, Dunn DT, Ceccherini-Silberstein F, De Mendoza C, Garcia F, Smit E, Fearnhill E, Marcelin AG, Martinez-Picado J, Kaiser R, Geretti AM. Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades. J Antimicrob Chemother 2015; 70(11): 3080-6. PubMed 

Herwartz C, Castillo-Juarez P, Schroder L, Barron BL, Steger G. The Transcription Factor ZNF395 Is Required for the Maximal Hypoxic Induction of Proinflammatory Cytokines in U87-MG Cells. Mediators Inflamm 2015; 2015: 804264. PubMed 

De Luca A, Di Giambenedetto S, Lo Presti A, Sierra S, Prosperi M, Cella E, Giovanetti M, Torti C, Caudai C, Vicenti I, Saladini F, Almi P, Grima P, Blanc P, Fabbiani M, Rossetti B, Gagliardini R, Kaiser R, Ciccozzi M, Zazzi M. Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors. Open Forum Infect Dis 2015; 2(2): ofv043. PubMed 

Charpentier C, Camacho R, Ruelle J, Eberle J, Gurtler L, Pironti A, Sturmer M, Brun-Vezinet F, Kaiser R, Descamps D, Obermeier M. HIV-2EU-Supporting Standardized HIV-2 Drug-Resistance Interpretation in Europe: An Update. Clin Infect Dis 2015; 61(8): 1346-7. PubMed 

Lubke N, Di Cristanziano V, Sierra S, Knops E, Schülter E, Jensen B, Oette M, Lengauer T, Kaiser R. Proviral DNA as a Target for HIV-1 Resistance Analysis. Intervirology 2015; 58(3): 184-9. PubMed 

Rabenau HF, Bannert N, Berger A, Donoso Mantke O, Eberle J, Enders M, Fickenscher H, Grunert HP, Gurtler L, Heim A, Huzly D, Kaiser R, Korn K, Nick S, Kucherer C, Nubling M, Obermeier M, Panning M, Zeichhardt H. Nachweis einer Infektion mit Humanem Immundefizienzvirus (HIV): Serologisches Screening mit nachfolgender Bestätigungsdiagnostik durch Antikörper-basierte Testsysteme und/oder mittels HIV-Nukleinsäure-Nachweis. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2015; 58(8): 877-86. PubMed 

Wieland U, Brockmeyer NH, Kreuter A. A 9-Valent HPV Vaccine in Women. N Engl J Med 2015; 372(26): 2566. PubMed 

Grüll H, Klein F. Mögliche Strategien zur HIV-Prävention und -Therapie. MMW Fortschr Med 2015; 157 Suppl 2: 46-9. PubMed 

Sierra S, Dybowski JN, Pironti A, Heider D, Guney L, Thielen A, Reuter S, Esser S, Fatkenheuer G, Lengauer T, Hoffmann D, Pfister H, Jensen B, Kaiser R. Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc. PLoS One 2015; 10(5): e0125502. PubMed 

Batinica M, Akgül B, Silling S, Mauch C, Zigrino P. Correlation of Merkel cell polyomavirus positivity with PDGFRalpha mutations and survivin expression in Merkel cell carcinoma. J Dermatol Sci 2015; 79(1): 43-9. PubMed 

Koksal MO, Beka H, Lübke N, Verheyen J, Eraksoy H, Cagatay A, Kaiser R, Akgül B, Agacfidan A. HIV-1 subtypes and drug resistance profiles in a cohort of heterosexual patients in Istanbul, Turkey. Med Microbiol Immunol 2015; 204(4): 551-5. PubMed 

Schmidt SV, Seibert S, Walch-Ruckheim B, Vicinus B, Kamionka EM, Pahne-Zeppenfeld J, Solomayer EF, Kim YJ, Bohle RM, Smola S. RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1alpha release, and efficient paracrine dendritic cell activation. Oncotarget 2015; 6(11): 8635-47. PubMed 

Pfister H. Association between betapapillomavirus seropositivity and keratinocyte carcinoma-prospects for prophylactic vaccination? J Invest Dermatol 2015; 135(5): 1211-3. PubMed 

Wieland U, Kreuter A. [HPV-induced anal lesions]. Hautarzt 2015; 66(6): 439-45. PubMed 

Caskey M, Klein F, Lorenzi JC, Seaman MS, West AP, Jr., Buckley N, Kremer G, Nogueira L, Braunschweig M, Scheid JF, Horwitz JA, Shimeliovich I, Ben-Avraham S, Witmer-Pack M, Platten M, Lehmann C, Burke LA, Hawthorne T, Gorelick RJ, Walker BD, Keler T, Gulick RM, Fatkenheuer G, Schlesinger SJ, Nussenzweig MC. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature 2015; 522(7557): 487-91. PubMed 

Kreuter A, van Eijk T, Lehmann P, Fischer M, Horn T, Assaf C, Schley G, Herbst R, Kellner I, Weisbrich C, Hyun J, Wieland U, Schlaak M, Rubben A, Lommel K. Electrochemotherapy in advanced skin tumors and cutaneous metastases - a retrospective multicenter analysis. J Dtsch Dermatol Ges 2015; 13(4): 308-15. PubMed 

Pironti A, Sierra S, Kaiser R, Lengauer T, Pfeifer N. Effects of sequence alterations on results from genotypic tropism testing. J Clin Virol 2015; 65: 68-73. PubMed 

Teutsch K, Schweitzer F, Knops E, Kaiser R, Pfister H, Verheyen J, Gobel H, Cingoz T, Di Cristanziano V. Early identification of renal transplant recipients with high risk of polyomavirus-associated nephropathy. Med Microbiol Immunol 2015; 204(6): 657-64. PubMed 

Swartz JE, Vandekerckhove L, Ammerlaan H, de Vries AC, Begovac J, Bierman WF, Boucher CA, van der Ende ME, Grossman Z, Kaiser R, Levy I, Mudrikova T, Paredes R, Perez-Bercoff D, Pronk M, Richter C, Schmit JC, Vercauteren J, Zazzi M, Zidovec Lepej S, De Luca A, Wensing AM. Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients in Europe. J Antimicrob Chemother 2015; 70(6): 1850-7. PubMed 

Howley PM, Pfister HJ. Beta genus papillomaviruses and skin cancer. Virology 2015; 479-480: 290-6. PubMed 

Verheyen J, Maizus K, Feist E, Tolman Z, Knops E, Saech J, Spengler L, Waterboer T, Burmester GR, Pawlita M, Pfister H, Rubbert-Roth A. Increased frequency of JC-polyomavirus detection in rheumatoid arthritis patients treated with multiple biologics. Med Microbiol Immunol 2015; 204(5): 613-8. PubMed 

Hübbers CU, Akgül B. HPV and cancer of the oral cavity. Virulence 2015; 6(3): 244-8. PubMed 

Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath MJ, Lehmann C, Klein F, Caskey M, Walker BD, Siliciano JD, Siliciano RF, Jankovic M, Nussenzweig MC. HIV-1 integration landscape during latent and active infection. Cell 2015; 160(3): 420-32. PubMed 

Kreuter A, Esser S, Wieland U. Anal cancer screening. J Am Acad Dermatol 2015; 72(2): 367-8. PubMed 

Vingerhoets J, Calvez V, Flandre P, Marcelin AG, Ceccherini-Silberstein F, Perno CF, Mercedes Santoro M, Bateson R, Nelson M, Cozzi-Lepri A, Grarup J, Lundgren J, Incardona F, Kaiser R, Sonnerborg A, Clotet B, Paredes R, Gunthard HF, Ledergerber B, Hoogstoel A, Nijs S, Tambuyzer L, Lavreys L, Opsomer M. Efficacy of etravirine combined with darunavir or other ritonavir-boosted protease inhibitors in HIV-1-infected patients: an observational study using pooled European cohort data. HIV Med 2015; 16(5): 297-306. PubMed 

Geipel A, Seiz PL, Niekamp H, Neumann-Fraune M, Zhang K, Kaiser R, Protzer U, Gerlich WH, Glebe D. Entecavir allows an unexpectedly high residual replication of HBV mutants resistant to lamivudine. Antivir Ther 2015; 20(8): 779-87. PubMed 

Pilatz A, Hossain H, Kaiser R, Mankertz A, Schuttler CG, Domann E, Schuppe HC, Chakraborty T, Weidner W, Wagenlehner F. Acute epididymitis revisited: impact of molecular diagnostics on etiology and contemporary guideline recommendations. Eur Urol 2015; 68(3): 428-35. PubMed 

Edwards S, Stucki H, Bader J, Vidal V, Kaiser R, Battegay M, Klimkait T. A diagnostic HIV-1 tropism system based on sequence relatedness. J Clin Microbiol 2015; 53(2): 597-610. PubMed 

Salpini R, Colagrossi L, Bellocchi MC, Surdo M, Becker C, Alteri C, Aragri M, Ricciardi A, Armenia D, Pollicita M, Di Santo F, Carioti L, Louzoun Y, Mastroianni CM, Lichtner M, Paoloni M, Esposito M, D'Amore C, Marrone A, Marignani M, Sarrecchia C, Sarmati L, Andreoni M, Angelico M, Verheyen J, Perno CF, Svicher V. Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression. Hepatology 2015; 61(3): 823-33. PubMed 

Ding X, Lucas T, Marcuzzi GP, Pfister H, Eming SA. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res 2015; 75(2): 330-43. PubMed 

Wiesmann F, Naeth G, Sarrazin C, Berger A, Kaiser R, Ehret R, Knechten H, Braun P. Variation analysis of six HCV viral load assays using low viremic HCV samples in the range of the clinical decision points for HCV protease inhibitors. Med Microbiol Immunol 2015; 204(4): 515-25. PubMed 

Cozzi-Lepri A, Noguera-Julian M, Di Giallonardo F, Schuurman R, Däumer M, Aitken S, Ceccherini-Silberstein F, D'Arminio Monforte A, Geretti AM, Booth CL, Kaiser R, Michalik C, Jansen K, Masquelier B, Bellecave P, Kouyos RD, Castro E, Furrer H, Schultze A, Gunthard HF, Brun-Vezinet F, Paredes R, Metzner KJ. Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing. J Antimicrob Chemother 2015; 70(3): 930-40. PubMed 

Olthof NC, Huebbers CU, Kolligs J, Henfling M, Ramaekers FC, Cornet I, van Lent-Albrechts JA, Stegmann AP, Silling S, Wieland U, Carey TE, Walline HM, Gollin SM, Hoffmann TK, de Winter J, Kremer B, Klussmann JP, Speel EJ. Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines. Int J Cancer 2015; 136(5): E207-18. PubMed 

Grund S, Gkioule C, Termos T, Pfeifer N, Kobbe G, Verheyen J, Adams O. Primarily oseltamivir-resistant influenza A (H1N1pdm09) virus evolving into a multidrug-resistant virus carrying H275Y and I223R neuraminidase substitutions. Antivir Ther 2015; 20(1): 97-100. PubMed 

Rodel F, Wieland U, Fraunholz I, Kitz J, Rave-Frank M, Wolff HA, Weiss C, Wirtz R, Balermpas P, Fokas E, Rodel C. Human papillomavirus DNA load and p16INK4a expression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy. Int J Cancer 2015; 136(2): 278-88. PubMed

2014

Gross G, Becker N, Brockmeyer NH, Esser S, Freitag U, Gebhardt M, Gissmann L, Hillemanns P, Grundhewer H, Ikenberg H, Jessen H, Kaufmann A, Klug S, Klussmann JP, Nast A, Pathirana D, Petry KU, Pfister H, Rollinghof U, Schneede P, Schneider A, Selka E, Singer S, Smola S, Sporbeck B, von Knebel Doeberitz M, Wutzler P. Vaccination against HPV-Associated Neoplasias: Recommendations from the Current S3 Guideline of the HPV Management Forum of the Paul-Ehrlich Society - AWMF Guidelines, Registry No. 082-002 (short version), valid until Dec. 31st, 2018. Geburtshilfe Frauenheilkd 2014; 74(3): 233-41. PubMed

Bao K, Akguel B, Bostanci N. Establishment and characterization of immortalized gingival epithelial and fibroblastic cell lines for the development of organotypic cultures. Cells Tissues Organs 2014; 199(4): 228-37. PubMed

Gross G, Becker N, Brockmeyer NH, Esser S, Freitag U, Gebhardt M, Gissmann L, Hillemanns P, Grundhewer H, Ikenberg H, Jessen H, Kaufmann A, Klug S, Klussmann JP, Nast A, Pathirana D, Petry KU, Pfister H, Rollinghof U, Schneede P, Schneider A, Selka E, Singer S, Smola S, Sporbeck B, von Knebel Doeberitz M, Wutzler P. [Vaccination against HPV-associated neoplasias]. Laryngorhinootologie 2014; 93(12): 848-56. PubMed

Schülter E, Kaiser R, Zazzi M, Sonnerborg A, Camacho R, Verheyen J. Time on drug analysis based on real life data. J Int AIDS Soc 2014; 17(4 Suppl 3): 19790. PubMed www.ncbi.nlm.nih.gov/pubmed/25397534

Pironti A, Pfeifer N, Kaiser R, Walter H, Lengauer T. Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences. J Int AIDS Soc 2014; 17(4 Suppl 3): 19743. PubMed

Schweitzer F, Mikkola V, Timmen-Wego M, Jensen B, Fatkenheuer G, Kaiser R. Longitudinal comparison of HIV-1 plasma viral load and cellular proviral load. J Int AIDS Soc 2014; 17(4 Suppl 3): 19669. PubMed

Klein F, Nogueira L, Nishimura Y, Phad G, West AP, Jr., Halper-Stromberg A, Horwitz JA, Gazumyan A, Liu C, Eisenreich TR, Lehmann C, Fatkenheuer G, Williams C, Shingai M, Martin MA, Bjorkman PJ, Seaman MS, Zolla-Pazner S, Karlsson Hedestam GB, Nussenzweig MC. Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants. J Exp Med 2014; 211(12): 2361-72. PubMed

Bournazos S, Klein F, Pietzsch J, Seaman MS, Nussenzweig MC, Ravetch JV. Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity. Cell 2014; 158(6): 1243-53. PubMed

Kordelas L, Verheyen J, Beelen DW, Horn PA, Heinold A, Kaiser R, Trenschel R, Schadendorf D, Dittmer U, Esser S. Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutation. N Engl J Med 2014; 371(9): 880-2. PubMed

Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P, Diskin R, Bjorkman PJ, Eckhaus MA, Klein F, Mouquet H, Cetrulo Lorenzi JC, Gazumyan A, Burton DR, Nussenzweig MC, Martin MA, Nishimura Y. Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. J Exp Med 2014; 211(10): 2061-74. PubMed

Halper-Stromberg A, Lu CL, Klein F, Horwitz JA, Bournazos S, Nogueira L, Eisenreich TR, Liu C, Gazumyan A, Schaefer U, Furze RC, Seaman MS, Prinjha R, Tarakhovsky A, Ravetch JV, Nussenzweig MC. Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice. Cell 2014; 158(5): 989-99. PubMed

Neogi U, Rao SD, Bontell I, Verheyen J, Rao VR, Gore SC, Soni N, Shet A, Schülter E, Ekstrand ML, Wondwossen A, Kaiser R, Madhusudhan MS, Prasad VR, Sonnerborg A. Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients. AIDS 2014; 28(15): 2319-22. PubMed

Neumann-Fraune M, Beggel B, Kaiser R, Obermeier M. Hepatitis B virus drug resistance tools: one sequence, two predictions. Intervirology 2014; 57(3-4): 232-6. PubMed

Yoldas O, Agacfidan A, Lübke N, Somer A, Hancerli S, Verheyen J, Kaiser R, Akgül B. Determination of drug resistance and virus typology in HIV-1-positive pediatric patients in Istanbul, Turkey. Intervirology 2014; 57(5): 297-9. PubMed

Lengauer T, Pfeifer N, Kaiser R. Personalized HIV therapy to control drug resistance. Drug Discov Today Technol 2014; 11: 57-64. PubMed

Gruell H, Klein F. Opening Fronts in HIV Vaccine Development: Tracking the development of broadly neutralizing antibodies. Nat Med 2014; 20(5): 478-9. PubMed

Wieland U, Kreuter A, Pfister H. Human papillomavirus and immunosuppression. Curr Probl Dermatol 2014; 45: 154-65. PubMed

Olthof NC, Speel EJ, Kolligs J, Haesevoets A, Henfling M, Ramaekers FC, Preuss SF, Drebber U, Wieland U, Silling S, Lam WL, Vucic EA, Kremer B, Klussmann JP, Huebbers CU. Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression. PloS one 2014; 9(2): e88718. PubMed

Broekaert SM, Ehrchen J, Buttner R, Pfister HJ, Metze D. Acquired epidermodysplasia verruciformis in an HIV-infected patient. J Dtsch Dermatol Ges 2014; 12(4): 353-5. PubMed

Nguyen T, Xu J, Chikuma S, Hiai H, Kinoshita K, Moriya K, Koike K, Marcuzzi GP, Pfister H, Honjo T, Kobayashi M. Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models. Int Immunol 2014; 26(7): 397-406. PubMed

West AP, Jr., Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC. Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell 2014; 156(4): 633-48. PubMed

Marcuzzi GP, Awerkiew S, Hufbauer M, Schadlich L, Gissmann L, Eming S, Pfister H. Tumor prevention in HPV8 transgenic mice by HPV8-E6 DNA vaccination. Med Microbiol Immunol 2014; 203(3): 155-63. PubMed

Wieland U, Silling S, Hellmich M, Potthoff A, Pfister H, Kreuter A. Human polyomaviruses 6, 7, 9, 10 and Trichodysplasia spinulosa-associated polyomavirus in HIV-infected men. J Gen Virol 2014; 95(Pt 4): 928-32. PubMed

Silling S, Wieland U, Werner M, Pfister H, Potthoff A, Kreuter A. Resolution of novel human papillomavirus-induced warts after HPV vaccination. Emerg Infect Dis 2014; 20(1): 142-5. PubMed

Malchers F, Dietlein F, Schottle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, Leenders F, Richters A, Peifer M, Florin A, Mainkar PS, Karre N, Chandrasekhar S, George J, Silling S, Rauh D, Zander T, Ullrich RT, Reinhardt HC, Ringeisen F, Buttner R, Heukamp LC, Wolf J, Thomas RK. Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer. Cancer Discov 2014; 4(2): 246-57. PubMed

Di Cristanziano V, Santoro M, Parisi F, Albonico M, Shaali MA, Di Cave D, Berrilli F. Genetic characterization of Giardia duodenalis by sequence analysis in humans and animals in Pemba Island, Tanzania. Parasitol Int 2014; 63(2): 438-41. PubMed

Krawczyk A, Hintze C, Ackermann J, Goitowski B, Trippler M, Gruner N, Neumann-Fraune M, Verheyen J, Fiedler M. Clinical performance of the novel DiaSorin LIAISON((R)) XL murex: HBsAg Quant, HCV-Ab, HIV-Ab/Ag assays. J Clin Virol 2014; 59(1): 44-9. PubMed

Iannacone MR, Gheit T, Pfister H, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Silling S, Pawlita M, Tommasino M, Rollison DE. Case-control study of genus-beta human papillomaviruses in plucked eyebrow hairs and cutaneous squamous cell carcinoma. Int J Cancer 2014; 134(9): 2231-44. PubMed

Pahne-Zeppenfeld J, Schroer N, Walch-Ruckheim B, Oldak M, Gorter A, Hegde S, Smola S. Cervical cancer cell-derived interleukin-6 impairs CCR7-dependent migration of MMP-9-expressing dendritic cells. Int J Cancer 2014; 134(9): 2061-73. PubMed

Mooren JJ, Gultekin SE, Straetmans JM, Haesevoets A, Peutz-Kootstra CJ, Huebbers CU, Dienes HP, Wieland U, Ramaekers FC, Kremer B, Speel EJ, Klussmann JP. P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. Int J Cancer 2014; 134(9): 2108-17. PubMed

2013

Beggel B, Neumann-Fraune M, Kaiser R, Verheyen J, Lengauer T. Inferring short-range linkage information from sequencing chromatograms. PLoS One 2013; 8(12): e81687. PubMed

Malbec M, Porrot F, Rua R, Horwitz J, Klein F, Halper-Stromberg A, Scheid JF, Eden C, Mouquet H, Nussenzweig MC, Schwartz O. Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission. J Exp Med 2013; 210(13): 2813-21. PubMed

Oette M, Reuter S, Kaiser R, Jensen B, Lengauer T, Fatkenheuer G, Knechten H, Hower M, Sagir A, Pfister H, Haussinger D. Ambulatory care for HIV-infected patients: differences in outcomes between hospital-based units and private practices: analysis of the RESINA cohort. Eur J Med Res 2013; 18: 48. PubMed

Tu E, Swenson LC, Land S, Pett S, Emery S, Marks K, Kelleher AD, Kaye S, Kaiser R, Schuelter E, Harrigan R. Reply to "Issues on results of the external quality assessment for proviral DNA testing of HIV-1 Tropism in the Maraviroc Switch collaborative study". J Clin Microbiol 2013; 51(12): 4287. PubMed

Bartha I, Assel M, Sloot PM, Zazzi M, Torti C, Schülter E, De Luca A, Sonnerborg A, Abecasis AB, Van Laethem K, Rosi A, Svard J, Paredes R, van de Vijver DA, Vandamme AM, Müller V. Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort. BMC Infect Dis 2013; 13: 537. PubMed

Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, Smith JY, Blackmore S, Sanisetty S, Perry JR, Beck M, Lewis MG, Rinaldi W, Chakraborty AK, Poignard P, Nussenzweig MC, Burton DR. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature 2013; 503(7475): 224-8. PubMed

Shingai M, Nishimura Y, Klein F, Mouquet H, Donau OK, Plishka R, Buckler-White A, Seaman M, Piatak M, Jr., Lifson JD, Dimitrov DS, Nussenzweig MC, Martin MA. Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia. Nature 2013; 503(7475): 277-80. PubMed

Schelhorn SE, Fischer M, Tolosi L, Altmüller J, Nürnberg P, Pfister H, Lengauer T, Berthold F. Sensitive detection of viral transcripts in human tumor transcriptomes. PLoS Comput Biol 2013; 9(10): e1003228. PubMed

Jordanovski D, Herwartz C, Pawlowski A, Taute S, Frommolt P, Steger G. The hypoxia-inducible transcription factor ZNF395 is controlled by IkB kinase-signaling and activates genes involved in the innate immune response and cancer. PLoS One 2013; 8(9): e74911. PubMed

Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Buning H, Schwartz O, Knops E, Kaiser R, Seaman MS, Wilson JM, Rice CM, Ploss A, Bjorkman PJ, Klein F, Nussenzweig MC. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc Natl Acad Sci U S A 2013; 110(41): 16538-43. PubMed

Gaebler C, Gruell H, Velinzon K, Scheid JF, Nussenzweig MC, Klein F. Isolation of HIV-1-reactive antibodies using cell surface-expressed gp160Deltac(BaL.). J Immunol Methods 2013; 397(1-2): 47-54. PubMed

Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC. Antibodies in HIV-1 vaccine development and therapy. Science 2013; 341(6151): 1199-204. PubMed

Hufbauer M, Biddle A, Borgogna C, Gariglio M, Doorbar J, Storey A, Pfister H, Mackenzie I, Akgül B. Expression of betapapillomavirus oncogenes increases the number of keratinocytes with stem cell-like properties. J Virol 2013; 87(22): 12158-65. PubMed

Cento V, Van Hemert F, Neumann-Fraune M, Mirabelli C, Di Maio VC, Salpini R, Bertoli A, Micheli V, Gubertini G, Romano S, Visca M, De Sanctis GM, Berkhout B, Marino N, Mazzotta F, Cappiello G, Spano A, Sarrecchia C, Ceccherini-Silberstein F, Andreoni M, Angelico M, Verheyen J, Perno CF, Svicher V. Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen. J Infect 2013; 67(4): 303-12. PubMed

West AP, Jr., Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ. Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. Proc Natl Acad Sci U S A 2013; 110(26): 10598-603. PubMed

Diskin R, Klein F, Horwitz JA, Halper-Stromberg A, Sather DN, Marcovecchio PM, Lee T, West AP, Jr., Gao H, Seaman MS, Stamatatos L, Nussenzweig MC, Bjorkman PJ. Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies. J Exp Med 2013; 210(6): 1235-49. PubMed

Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jeze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, Klein F, Swiecki M, Colonna M, Kamphorst AO, Meredith M, Niec R, Takacs C, Mikhail F, Hari A, Bosque D, Eisenreich T, Merad M, Shi Y, Ginhoux F, Renia L, Urban BC, Nussenzweig MC. Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection. Nat Med 2013; 19(6): 730-8. PubMed

Ehlers B, Wieland U. The novel human polyomaviruses HPyV6, 7, 9 and beyond. Apmis 2013; 121(8): 783-95. PubMed

Libin P, Beheydt G, Deforche K, Imbrechts S, Ferreira F, Van Laethem K, Theys K, Carvalho AP, Cavaco-Silva J, Lapadula G, Torti C, Assel M, Wesner S, Snoeck J, Ruelle J, De Bel A, Lacor P, De Munter P, Van Wijngaerden E, Zazzi M, Kaiser R, Ayouba A, Peeters M, de Oliveira T, Alcantara LC, Grossman Z, Sloot P, Otelea D, Paraschiv S, Boucher C, Camacho RJ, Vandamme AM. RegaDB: community-driven data management and analysis for infectious diseases. Bioinformatics 2013; 29(11): 1477-80. PubMed

Vercauteren J, Beheydt G, Prosperi M, Libin P, Imbrechts S, Camacho R, Clotet B, De Luca A, Grossman Z, Kaiser R, Sonnerborg A, Torti C, Van Wijngaerden E, Schmit JC, Zazzi M, Geretti AM, Vandamme AM, Van Laethem K. Clinical evaluation of Rega 8: an updated genotypic interpretation system that significantly predicts HIV-therapy response. PLoS One 2013; 8(4): e61436. PubMed

Kreuter A, Wieland U, Hampl M. Recurrent high-risk human papillomavirus-induced anogenital dysplasia in chronic idiopathic CD4+ T lymphocytopaenia. Acta Derm Venereol 2013; 93(6): 759-60. PubMed

Tu E, Swenson LC, Land S, Pett S, Emery S, Marks K, Kelleher AD, Kaye S, Kaiser R, Schuelter E, Harrigan R. Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc Switch collaborative study. J Clin Microbiol 2013; 51(7): 2063-71. PubMed

Rolfs F, Huber M, Gruber F, Bohm F, Pfister HJ, Bochkov VN, Tschachler E, Dummer R, Hohl D, Schafer M, Werner S. Dual role of the antioxidant enzyme peroxiredoxin 6 in skin carcinogenesis. Cancer Res 2013; 73(11): 3460-9. PubMed

Bozek K, Lengauer T, Sierra S, Kaiser R, Domingues FS. Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage. PLoS Comput Biol 2013; 9(3): e1002977. PubMed

Klein F, Diskin R, Scheid JF, Gaebler C, Mouquet H, Georgiev IS, Pancera M, Zhou T, Incesu RB, Fu BZ, Gnanapragasam PN, Oliveira TY, Seaman MS, Kwong PD, Bjorkman PJ, Nussenzweig MC. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell 2013; 153(1): 126-38. PubMed

Wieland U, Kreuter A. One step towards standardised management of anal dysplasia. Lancet Oncol 2013; 14(4): 273-4. PubMed

Huebbers CU, Preuss SF, Kolligs J, Vent J, Stenner M, Wieland U, Silling S, Drebber U, Speel EJ, Klussmann JP. Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis. PLoS One 2013; 8(2): e57207. PubMed

Charpentier C, Camacho R, Ruelle J, Kaiser R, Eberle J, Gurtler L, Pironti A, Sturmer M, Brun-Vezinet F, Descamps D, Obermeier M. HIV-2EU: supporting standardized HIV-2 drug resistance interpretation in Europe. Clin Infect Dis 2013; 56(11): 1654-8. PubMed

Neumann-Fraune M, Beggel B, Pfister H, Kaiser R, Verheyen J. High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates. J Med Virol 2013; 85(5): 775-9. PubMed

Neale RE, Weissenborn S, Abeni D, Bavinck JN, Euvrard S, Feltkamp MC, Green AC, Harwood C, de Koning M, Naldi L, Nindl I, Pawlita M, Proby C, Quint WG, Waterboer T, Wieland U, Pfister H. Human papillomavirus load in eyebrow hair follicles and risk of cutaneous squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2013; 22(4): 719-27. PubMed

De Luca A, Dunn D, Zazzi M, Camacho R, Torti C, Fanti I, Kaiser R, Sonnerborg A, Codoner FM, Van Laethem K, Vandamme AM, Bansi L, Ghisetti V, van de Vijver DA, Asboe D, Prosperi MC, Di Giambenedetto S. Declining prevalence of HIV-1 drug resistance in antiretroviral treatment-exposed individuals in Western Europe. J Infect Dis 2013; 207(8): 1216-20. PubMed

Hoot S, McGuire AT, Cohen KW, Strong RK, Hangartner L, Klein F, Diskin R, Scheid JF, Sather DN, Burton DR, Stamatatos L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. PLoS Pathog 2013; 9(1): e1003106. PubMed

Alpsar D, Agacfidan A, Lübke N, Verheyen J, Eraksoy H, Cagatay A, Bozkaya E, Kaiser R, Akgül B. Molecular epidemiology of HIV in a cohort of men having sex with men from Istanbul. Med Microbiol Immunol 2013; 202(3): 251-5. PubMed

Kreuter A, Wieland U. Lack of efficacy in treating condyloma acuminata and preventing recurrences with the recombinant quadrivalent human papillomavirus vaccine in a case series of immunocompetent patients. J Am Acad Dermatol 2013; 68(1): 179-80. PubMed

Theys K, Vercauteren J, Snoeck J, Zazzi M, Camacho RJ, Torti C, Schülter E, Clotet B, Sonnerborg A, De Luca A, Grossman Z, Struck D, Vandamme AM, Abecasis AB. HIV-1 subtype is an independent predictor of reverse transcriptase mutation K65R in HIV-1 patients treated with combination antiretroviral therapy including tenofovir. Antimicrob Agents Chemother 2013; 57(2): 1053-6. PubMed

Antonsson A, Waterboer T, Bouwes Bavinck JN, Abeni D, de Koning M, Euvrard S, Feltkamp MC, Green AC, Harwood CA, Naldi L, Nindl I, Pfister HJ, Proby CM, Quint WG, Stockfleth E, Weissenborn SJ, Pawlita M, Neale RE. Longitudinal study of seroprevalence and serostability of 34 human papillomavirus types in European organ transplant recipients. Virology 2013; 436(1): 91-9. PubMed

2012

Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, Mouquet H, Spatz LA, Diskin R, Abadir A, Zang T, Dorner M, Billerbeck E, Labitt RN, Gaebler C, Marcovecchio PM, Incesu RB, Eisenreich TR, Bieniasz PD, Seaman MS, Bjorkman PJ, Ravetch JV, Ploss A, Nussenzweig MC. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature 2012; 492(7427): 118-22. PubMed

Pietzsch J, Gruell H, Bournazos S, Donovan BM, Klein F, Diskin R, Seaman MS, Bjorkman PJ, Ravetch JV, Ploss A, Nussenzweig MC. A mouse model for HIV-1 entry. Proc Natl Acad Sci U S A 2012; 109(39): 15859-64. PubMed

Schulmann K, Strate K, Pox CP, Wieland U, Kreuter A. Paraneoplastic acanthosis nigricans with cutaneous and mucosal papillomatosis preceding recurrence of a gastric adenocarcinoma. J Clin Oncol 2012; 30(32): e325-6. PubMed

Scola N, Skrygan M, Wieland U, Kreuter A, Gambichler T. Altered gene expression in squamous cell carcinoma arising from congenital unilateral linear porokeratosis. Clin Exp Dermatol 2012; 37(7): 781-5. PubMed

Sather DN, Carbonetti S, Kehayia J, Kraft Z, Mikell I, Scheid JF, Klein F, Stamatatos L. Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus. J Virol 2012; 86(23): 12676-85. PubMed

Buitrago-Perez A, Hachimi M, Duenas M, Lloveras B, Santos A, Holguin A, Duarte B, Santiago JL, Akgül B, Rodriguez-Peralto JL, Storey A, Ribas C, Larcher F, del Rio M, Paramio JM, Garcia-Escudero R. A humanized mouse model of HPV-associated pathology driven by E7 expression. PLoS One 2012; 7(7): e41743. PubMed

Sperling T, Oldak M, Walch-Ruckheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S. Human papillomavirus type 8 interferes with a novel C/EBPbeta-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration. PLoS Pathog 2012; 8(7): e1002833. PubMed

Fun A, Wensing AM, Verheyen J, Nijhuis M. Human Immunodeficiency Virus Gag and protease: partners in resistance. Retrovirology 2012; 9: 63. PubMed

Bozek K, Eckhardt M, Sierra S, Anders M, Kaiser R, Kräusslich HG, Müller B, Lengauer T. An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data. Retrovirology 2012; 9: 60. PubMed

Klein F, Gaebler C, Mouquet H, Sather DN, Lehmann C, Scheid JF, Kraft Z, Liu Y, Pietzsch J, Hurley A, Poignard P, Feizi T, Morris L, Walker BD, Fatkenheuer G, Seaman MS, Stamatatos L, Nussenzweig MC. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. J Exp Med 2012; 209(8): 1469-79. PubMed

Scola N, Wieland U, Silling S, Altmeyer P, Stucker M, Kreuter A. Prevalence of human polyomaviruses in common and rare types of non-Merkel cell carcinoma skin cancer. Br J Dermatol 2012; 167(6): 1315-20. PubMed

Kaiser R, Wensing AM. HIV co-receptor tropism: old target for new therapeutic strategies. Curr Opin HIV AIDS 2012; 7(5): 429-31. PubMed

Potthoff A, Wieland U, Kreuter A. Failure of intravenous cidofovir for generalized verrucosis in a patient with severe combined immunodeficiency. Arch Dermatol 2012; 148(5): 659-60. PubMed

Mikolajczak S, Quante G, Weissenborn S, Wafaisade A, Wieland U, Luers JC, Klussmann JP, Beutner D. The impact of cidofovir treatment on viral loads in adult recurrent respiratory papillomatosis. Eur Arch Otorhinolaryngol 2012; 269(12): 2543-8. PubMed

Beggel B, Neumann-Fraune M, Doring M, Lawyer G, Kaiser R, Verheyen J, Lengauer T. Genotyping hepatitis B virus dual infections using population-based sequence data. J Gen Virol 2012; 93(Pt 9): 1899-907. PubMed

Schmitt M, Wieland U, Kreuter A, Pawlita M. C-terminal deletions of Merkel cell polyomavirus large T-antigen, a highly specific surrogate marker for virally induced malignancy. Int J Cancer 2012; 131(12): 2863-8. PubMed

Lazic D, Hufbauer M, Zigrino P, Buchholz S, Kazem S, Feltkamp MC, Mauch C, Steger G, Pfister H, Akgül B. Human papillomavirus type 8 E6 oncoprotein inhibits transcription of the PDZ protein syntenin-2. J Virol 2012; 86(15): 7943-52. PubMed

Verheyen J, Neumann-Fraune M, Berg T, Kaiser R, Obermeier M. The detection of HBsAg mutants expressed in vitro using two different quantitative HBsAg assays. J Clin Virol 2012; 54(3): 279-81. PubMed

Rhee SY, Blanco JL, Liu TF, Pere I, Kaiser R, Zazzi M, Incardona F, Towner W, Gatell JM, De Luca A, Fessel WJ, Shafer RW. Standardized representation, visualization and searchable repository of antiretroviral treatment-change episodes. AIDS Res Ther 2012; 9(1): 13. PubMed

Verheyen J, Kaiser R, Bozic M, Timmen-Wego M, Maier BK, Kessler HH. Extraction of viral nucleic acids: comparison of five automated nucleic acid extraction platforms. J Clin Virol 2012; 54(3): 255-9. PubMed

Akgül B, Zigrino P, Hufbauer M, Liu X, Moore PS, Mauch C, Pfister H. Lack of integrin beta5 in Merkel cell carcinomas and derived cell lines is frequently associated with Merkel cell polyomavirus positivity. J Dermatol Sci 2012; 67(1): 66-8. PubMed

Rappl G, Riet T, Awerkiew S, Schmidt A, Hombach AA, Pfister H, Abken H. The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells. PLoS One 2012; 7(1): e30713. PubMed

Oette M, Schülter E, Rosen-Zvi M, Peres Y, Zazzi M, Sonnerborg A, Struck D, Altmann A, Kaiser R. Efficacy of antiretroviral therapy switch in HIV-infected patients: a 10-year analysis of the EuResist Cohort. Intervirology 2012; 55(2): 160-6. PubMed

Oette M, Reuter S, Kaiser R, Lengauer T, Fatkenheuer G, Knechten H, Hower M, Pfister H, Haussinger D. Epidemiology of transmitted drug resistance in chronically HIV-infected patients in Germany: the RESINA study 2001-2009. Intervirology 2012; 55(2): 154-9. PubMed

Zazzi M, Incardona F, Rosen-Zvi M, Prosperi M, Lengauer T, Altmann A, Sonnerborg A, Lavee T, Schülter E, Kaiser R. Predicting response to antiretroviral treatment by machine learning: the EuResist project. Intervirology 2012; 55(2): 123-7. PubMed

Obermeier M, Pironti A, Berg T, Braun P, Däumer M, Eberle J, Ehret R, Kaiser R, Kleinkauf N, Korn K, Kücherer C, Müller H, Noah C, Stürmer M, Thielen A, Wolf E, Walter H. HIV-GRADE: a publicly available, rules-based drug resistance interpretation algorithm integrating bioinformatic knowledge. Intervirology 2012; 55(2): 102-7. PubMed

Sierra-Aragon S, Walter H. Targets for inhibition of HIV replication: entry, enzyme action, release and maturation. Intervirology 2012; 55(2): 84-97. PubMed

Wieland U, Stuecker M, Kreuter A. HPV vaccine against anal intraepithelial neoplasia. N Engl J Med 2012; 366(4): 378; author reply -9. PubMed

Lawyer G, Schülter E, Kaiser R, Reuter S, Oette M, Lengauer T. Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort. Med Microbiol Immunol 2012; 201(3): 259-69. PubMed

Silling S, Kreuter A, Hellmich M, Swoboda J, Pfister H, Wieland U. Human papillomavirus oncogene mRNA testing for the detection of anal dysplasia in HIV-positive men who have sex with men. J Clin Virol 2012; 53(4): 325-31. PubMed

Borgogna C, Zavattaro E, De Andrea M, Griffin HM, Dell'Oste V, Azzimonti B, Landini MM, Peh WL, Pfister H, Doorbar J, Landolfo S, Gariglio M. Characterization of beta papillomavirus E4 expression in tumours from Epidermodysplasia Verruciformis patients and in experimental models. Virology 2012; 423(2): 195-204. PubMed

Knops E, Brakier-Gingras L, Schülter E, Pfister H, Kaiser R, Verheyen J. Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors. Med Microbiol Immunol 2012; 201(2): 213-8. PubMed

Vehreschild JJ, Moritz G, Vehreschild MJ, Arenz D, Mahne M, Bredenfeld H, Chemnitz J, Klein F, Cremer B, Boll B, Kaul I, Wassmer G, Hallek M, Scheid C, Cornely OA. Efficacy and safety of moxifloxacin as antibacterial prophylaxis for patients receiving autologous haematopoietic stem cell transplantation: a randomised trial. Int J Antimicrob Agents 2012; 39(2): 130-4. PubMed

Vehreschild JJ, Brockelmann PJ, Bangard C, Verheyen J, Vehreschild MJ, Michels G, Wisplinghoff H, Cornely OA. Pandemic 2009 influenza A(H1N1) virus infection coinciding with invasive pulmonary aspergillosis in neutropenic patients. Epidemiol Infect 2012; 140(10): 1848-52. PubMed

Svicher V, Cento V, Bernassola M, Neumann-Fraune M, Van Hemert F, Chen M, Salpini R, Liu C, Longo R, Visca M, Romano S, Micheli V, Bertoli A, Gori C, Ceccherini-Silberstein F, Sarrecchia C, Andreoni M, Angelico M, Ursitti A, Spano A, Zhang JM, Verheyen J, Cappiello G, Perno CF. Novel HBsAg markers tightly correlate with occult HBV infection and strongly affect HBsAg detection. Antiviral Res 2012; 93(1): 86-93. PubMed

Wieland U, Scola N, Stolte B, Stucker M, Silling S, Kreuter A. No evidence for a causal role of Merkel cell polyomavirus in keratoacanthoma. J Am Acad Dermatol 2012; 67(1): 41-6. PubMed

Kreuter A, Bechara FG, Stucker M, Brockmeyer NH, Altmeyer P, Wieland U. Perianal basal cell carcinoma - unusual localization of a frequent tumor. J Dtsch Dermatol Ges 2012; 10(1): 59-61. PubMed

Sampogna F, Bavinck JN, Pawlita M, Abeni D, Harwood CA, Proby CM, Feltkamp MC, Euvrard S, Naldi L, Neale RE, Nindl I, Pfister H, Quint WG, Waterboer T. Factors associated with the seroprevalence of 26 cutaneous and two genital human papillomavirus types in organ transplant patients. J Gen Virol 2012; 93(Pt 1): 165-74. PubMed

Akgül B, Pfister D, Knuchel R, Heidenreich A, Wieland U, Pfister H. No evidence for a role of xenotropic murine leukaemia virus-related virus and BK virus in prostate cancer of German patients. Med Microbiol Immunol 2012; 201(2): 245-8. PubMed

Weissenborn S, Neale RE, Waterboer T, Abeni D, Bavinck JN, Green AC, Harwood CA, Euvrard S, Feltkamp MC, de Koning MN, Naldi L, Quint WG, Tessari G, Proby CM, Wieland U, Pfister H. Beta-papillomavirus DNA loads in hair follicles of immunocompetent people and organ transplant recipients. Med Microbiol Immunol 2012; 201(2): 117-25. PubMed

Pastrana DV, Wieland U, Silling S, Buck CB, Pfister H. Positive correlation between Merkel cell polyomavirus viral load and capsid-specific antibody titer. Med Microbiol Immunol 2012; 201(1): 17-23. PubMed

Heger E, Thielen A, Gilles R, Obermeier M, Lengauer T, Kaiser R, Trapp S. APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1. Med Microbiol Immunol 2012; 201(1): 7-16. PubMed